
1990 PhD, Pharmacology, entitled "An investigation of the relationship between presynaptic a-adrenoceptors, uptake mechanism and the control of noradrenaline release", under the joint supervision of the Dept. of Pharmacology, School of Medicine, Univ. of Leeds, England, and the Dept. of Pharmacology, Faculty of Pharmacy, Alexandria Univ., Egypt.
1986 MSc, Pharmacology, entitled "Comparative study of some drugs used in treatment of experimental gastric ulceration", Dept. of Pharmacology, Faculty of Pharmacy, Alexandria Univ., Egypt.
1982 BS, Pharmacy, with the grade of Distinction Honor, Faculty of Pharmacy, Alexandria Univ., Egypt.
Career History
2020- Professor, Pharmacology and Toxicology, Faculty of Medicine, Kuwait Univ., Kuwait
2020- Professor Emeritus, Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria Univ., Egypt.
2000-2020 Professor, Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria Univ., Egypt.
2002-2004 Visiting Professor, Dept. of Pharmacology and Toxicology, School of Medicine, East Carolina Univ., Greenville, NC 27858, U.S.A
1996-1999 Visiting Professor, Dept. of Pharmacology and Toxicology, School of Medicine, East Carolina Univ., Greenville, NC 27858, U.S.A
1995-2000 Associate Professor, Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria Univ., Egypt.
1991-1993 Visiting Professor, Dept. of Pharmacology and Toxicology, School of Medicine, East Carolina Univ., Greenville, NC 27858, U.S.A
1990-1995 Assistant Professor, Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria Univ., Egypt.
1988-1990 Exchange graduate PhD student, Dept. of Pharmacology, School of Medicine, Univ. of Leeds, U.K. (PhD joint supervision scheme between Egypt and foreign countries).
1982-1990 Instructor, Pharmacology and Toxicology, Faculty of Pharmacy, Alexandria Univ., Egypt.
Academic and Research Experience Abroad
July 2018 A visit to the Department of Pharmacy, University of Pisa, Italy, on an Erasmus+ mobility grant, which was funded by the European Commission, between Alexandria University, Egypt, and University of Pisa, Italy.
Aug 2016 A visit to the Appalachian college of Pharmacy, Virginia, USA, as a representative of the Faculty of Pharmacy, Alexandria Univ., Egypt, to negotiate the terms of a “Memo of Understanding” on academic and research collaborations between the two institutions.
May 2015 An invited visit to the Faculty of Pharmacy, King Abdulaziz University, Saudie Arabia, to participate and lecture in a workshop entitled “Recent concepts on Cardiovascular Complications”.
Visiting Professor, Dept. of Pharmacology and Toxicology, School of Medicine, East Carolina Univ., Greenville, NC 27858, U.S.A, for more than 11 years during the following time periods:
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1988-1990 Exchange graduate PhD student, Dept. of Pharmacology, School of Medicine, Univ. of Leeds, U.K., according to the Ph.D. joint supervision scheme between Egypt and foreign countries.
Editorial Board Positions
2024- Deciding Editor, Naunyn-Schmiedeberg's Archives of Pharmacology
2020- Associate Editor, Frontiers in Pharmacology (section: Cardiovascular and Smooth Muscle Pharmacology)
2017- Editorial Board, Egyptian Journal of Basic and Clinical Pharmacology
2017- Editorial Board, The Open Access Journal of Science and Technology
2007- Pharmacy Times Middle East
2007- Editor, African Journal of Pharmacy and Pharmacology
Emeritus Editorial Board Positions
2013-2023 Advisory Editor, Naunyn-Schmiedeberg's Archives of Pharmacology
2015-2019 Consulting Editor, ChronoPhysiology and Therapy
2010-2015 Honorary Editorial Board, ChronoPhysiology and Therapy
2007-2009 Regional Editor Emeritus: International Journal of Pharmacology.
Awards & Honors
2018 Best Researcher Award, Clarivate Analytics & Egyptian Knowledge Bank.
2015/2016 Khalifa Award for Education, Distinguished University Professor in the Field of Scientific Research, United Arab Emirates (جائزة خليفة التربوية للأستاذ الجامعي المتميز في البحث العلمي) .
2016 ASPET Travel Award, Keynote speaker, Experimental Biology meeting, San Diego, California, U.S.A (April 2-6, 2016)
2011 Alexandria University Honorary Award (جائزة ﺠﺎﻤﻌﺔ الإسكندرية ﺍﻟﺗﻗﺪﻴﺮﻴﺔ), Egypt.
2010 Distinguished Research Professor, Alexandria Univ. (جائزة الأستاذ الباحث المتميز لجامعة الإسكندرية), Egypt.
2007 ACDIMA award for the Top Scientific Publication in Applied Pharmaceutical Sciences, Jordon.
2007 Biography enlisted in the “Marquis Who's Who in the World”, 25th Anniversary Edition, and in the “Marquis Who's Who in Science and Engineering”, 10th Anniversary Edition.
2006 Biography enlisted in the “Marquis Who’sWho in Medicine and Healthcare”, 6th Edition.
2006 State Prize for Scientific Excellence in Medical Sciences (ﻠﻠﺗﻓﻮﻖ جائزة الدولة), Egypt.
2006 Silver Appreciation Medal (الميدالية التقديرية الفضية), General Syndicate of Pharmacists, Egypt.
2002 Gold Appreciation Medal (الميدالية التقديرية الذهبية), General Syndicate of Pharmacists, Egypt.
2000 State Prize for Scientific Encouragement in Medical Sciences (جائزة الدولة التشجيعية), Egypt.
1994 State Prize for Scientific Encouragement in Medical Sciences (جائزة الدولة التشجيعية), Egypt.
1982 Egyptian Pharmaceutical Companies' Award for top graduate in pharmaceutical sciences.
1980 Alexandria University Student Union's Award for undergraduate scientific distinction.
Research Grants
Principal Investigator (PI)
PI, Research Grant, Research Sector, Kuwait University (MR01/22, Oct 2023 - Sep 2026), titled “Modulation of septic cardiovascular defects by remote ischemic preconditioning: sex and gonadal hormone traits” (85,000 Kuwaiti Dinars).
PI, Basic and Applied Science Research Grant, the Science and Technology Research Fund (STDF ID 14895, Nov 2015- Nov 2018), Ministry of higher Education, Egypt, " Sexual and molecular dimorphism in nicotine protection against renal and hemodynamic derangements of endotoxic shock” (763,400 L.E.).
PI, Alex-Rep Grant (HLTH-13-01, 2014-2016), Alexandria University, Egypt "Heme oxygenase modulation of cardiovascular derangements evoked by the combined cyclosporine/NSAIDs regimen in rats: Functional, structural, and molecular studies" (130,000 L.E.).
PI, Basic and Applied Science Research Grant, the Science and Technology Research Fund (STDF ID 502, May 2010- Nov 2013), Ministry of higher Education, Egypt, "Hemodynamic and renal effects of nicotine in rats with surgical menopause" (999,600 L.E.).
PI, Biomedical Research Support Grant from the School of Medicine, East Carolina University, North Carolina, U.S.A. (1992-1993) "Role of glutamate receptors in the depressant effect of ethanol on baroreflexes" (US$2,600).
PI, American Heart Association Research Grant (1992-1993; #NC-92-GB-4) "Functional interaction between aortic baroreceptors and central a2-adrenergic and imidazole receptors" (US$10,000).
Co-PI/Co-Investigator
Consultant, Grant No. 14-BIO929-03 (Jan 2018 – Jan 2020), National Science, Technology and Innovation Plan (NSTIP), strategic technologies program, Kingdom of Saudi Arabia “A novel nanoceutical formula of natural ingredients for cardiovascular complications of metabolic syndrome” (575,660 SR).
Co-PI, Grant No. 166-110-D1437 (Jan 2016 - Sep 2016), King Abdulaziz University, Saudie Arabia, “Sex-related cardiovascular consequences of chronic prenatal exposure to cyclosporine in rats.” (35,000 SR).
Co-PI, Grant No. 166-1001-D1435 (Jan 2015 - Sep 2015), King Abdulaziz University, Saudie Arabia, “Sexual dimorphism in cardiac performance and electrocardiographic alterations caused by chronic cyclosporine in rats” (35,000 SR).
Chief Advisor: The Lebanese National Council for Scientific Research Grant Award for Lebanese graduates (US$ 12,000, 2015-2017); PhD student: Safaa Hisham Hammoud, Faculty of Pharmacy, Beirut Arab University; Project title: Modulation of EDHF-mediated renovascular relaxation by CYP inducers/inhibitors in cyclosporine nephrotoxicity in rats.
Co-Investigator, National Institute on Alcohol abuse and alcoholism grant (AA07839, 1991-1993, 1996-1999, 2002-2004), U.S.A., "Negative impact of alcohol on antihypertensive medications".
Co-Investigator, National Institute on Alcohol abuse and alcoholism grant (AA10257, 1996-1999, 2002-2004), U.S.A., "Estrogen-dependent cardiovascular effect of ethanol".
Educational Grants
Member, Course Review and Quality Assurance Committee, ERASMUS PLUS multi-beneficiaries project funded by the European Union, entitled “IT-based international Diploma and professional certificates in clinical Toxicology” (561915-EPP-1-2015-1-EG-EPPKA2-CBHE-JP, 15-10-2015 till 15-4-2019, PI: Dr. Noha Fawzy Abdelkader, Faculty of Pharmacy, Cairo University, Egypt).
Mobility Grants
Staff mobility grant for training and research in the framework of the inter-institutional agreement 2016-2018 for the Erasmus+ International Credit Mobility, which was funded by the European Commission, between Alexandria University, Egypt, and University of Pisa, Italy (July 2018).
Academic and societal activities
2024 Member, Promotion Review Committee, Department of Microbiology, Faculty of Medicine, Kuwait University (Applicant: Haya Altawalah, Associate professorship promotion).
2024 Member, Promotion Review Committee, Department of Physiology, Faculty of Medicine, Kuwait University (Applicant: Fawzi Abdalla Babiker, full professorship promotion).
2023 Member, Promotion Review Committee, Department of Physiology, Faculty of Medicine, Kuwait University (Applicant: Dr. Abdeslam Mouihate, full professorship promotion).
2023 Member, Promotion Committee, Department of Pharmacology and Toxicology, College of pharmacy, King Saud University, Riyadh, Saudi Arabia (Applicant: Dr. Faleh Alqahtani, Associate professorship promotion).
2021 Member, Faculty Appointment Committee, Faculty of Pharmacy, Alalamein University, Egypt.
2021 Member, Promotion Review Committee, Department of Pharmacology and Therapeutics, Faculty of Pharmacy, Kuwait University (Applicant: Dr. Maitham Khajah to the rank of full professor).
2021-Present, Director, Pharmacology Graduate Programs Committee, Faculty of Medicine, Kuwait University.
2021-Present Member, Area Graduate Program Committee, Faculty of Medicine, Kuwait University.
2020- Member, Phase II Examination Committee, Faculty of Medicine, Kuwait University.
2018-2020 Chair, National Drug Committee (Academy of Scientific Research & Technology, Egypt).
2013-2016 Chair, National Committee on Academic Faculty Promotion (Pharmacology & Clinical Pharmacy).
2014-2017 Member, Pharmacology Promotion Committee (National Organization for Drug Control and Research).
2014-2018 Member, National Board for Pharmacology (Academy of Scientific Research & Technology).
2008-2013 Member, National Committee on Academic Faculty Promotion (Pharmacology).
Reviewer for reputable international journals including: Br J Pharmacol, Biochem Pharmacol, Neuropharmacology, J Pharmacol Exp Ther, Toxicol Appl Pharmacol, Am J Physiol Renal Physiol, Am J Physiol Renal Physiol, Reg Physiol, Am J Physiol Heart and Cir Physiol, Sci Rep, J Appl Physiol, J Neurochem, J Cell Biochem, Pharmacol Res, Frontiers in Cell and Developmental Biology, Curr Vasc Pharmacol, PLOS ONE, Neurosci Lett, Nauyn-Schmiedeberg's Arch Pharmacol, J Cardiovasc Pharmacol Ther, Brain Research, Life Sci, Journal of Reproductive Immunology, Hypertension Research, Eur J Pharmacol, Fundam Cardiovascular Therapeutics, Clin Pharmacol, Expert Rev Cardiovasc Ther, Clin Exp Pharmacol Physiol, Food Chem Tox, Pediatric Research, Saudi Pharmaceutical Journal, Biol Res Nurs, Int J Health Sci, North Am J Med Sci, Int J Pharmacol, Zag J Pharm Sci.
Scientific Evaluator (grants, promotions, awards):
Qatar National Research Fund (QNRF, 12 applications).
“Newton-Mosharafa Fund” applications for PhD missions, British Council (2018/2019)
The USA-Egypt Joint-Research Fund (2 applications).
The Science and Technology Development Fund, Egypt (STDF, 7 applications).
JESOR‐Development grants, Academy of Scientific Research and Technology, Egypt (2 applications)
National Awards, Academy of Scientific Research and Technology, Egypt (3 applications).
Award Applications, Tanta University (1 application).
Grant and award applications, Mansura University (6 applications).
Alex Rep project applications, Alexandria University (2 applications).
Faculty promotion applications, Supreme Council of Egyptian Universities, Egypt (28 applications)
Faculty promotion applications, Azhar University, Egypt (3 applications)
Faculty promotion applications, Atomic Energy Authority, Egypt (1 applications)
Faculty promotion applications, Nigeria University, Nigeria (3 applications).
Faculty promotion applications, University of Mosul, Iraq (2 Professorship applications).
Research Poster Evaluation, the 6th International Conference on Natural Toxins, Suez Canal University, Ismailia, Egypt (Dec 15-16, 2014).
Chair, Committee for reviewing Faculty Promotion Guidelines received from the Supreme Council of Egyptian Universities (2018)
Member, Faculty Selection Committee, Faculty of Pharmacy, Damanhour University.
Member, Committee on National Awards, Academy of Scientific Research and Technology, Egypt (2015)
Member, Scientific Ethics Committee, Alexandria University, Egypt (2009).
Sep 2016 Biological testing of eye drops manufactured by PHARCO Pharmaceuticals (Draize eye irritation test).
Continuing Education Program, Egyptian Syndicate of Pharmacists.
Scientific Consultant, PHARCO Pharmaceutical Co., Alexandria, Egypt (1994-1995).
Membership in Professional Societies
2018-2020, 2024- American Physiological Society (APS, membership No. 00218239).
2010- American Heart Association (AHA, membership No. 171315005).
2007- American Society for Pharmacology and Experimental Therapeutics (ASPET, membership No. 10604).
1985- Egyptian Society for Pharmacology and Experimental Therapeutics (ESPET).
1987- Egyptian Society for Toxicology.
1982- Egyptian Syndicate of Pharmacists
Pharmacology Graduate Mentorship (24 students)
PhD degrees
Salwa Aburageh Said Abuiessa (July 27, 2021), Faculty of Pharmacy, Alexandria Univ.
Marwa Youssef Sallam (July 27, 2020), Faculty of Pharmacy, Alexandria Univ.
Safaa Hisham Hammoud (November 16, 2017), Faculty of Pharmacy, Beirut Arab Univ., Lebanon
Suzanne Aunni Naser (June 19, 2014), Faculty of Pharmacy, Beirut Arab Univ., Lebanon
Mohamed Amin Fouda (May 18, 2014), Faculty of Pharmacy, Alexandria Univ.
Eman Yousry Gohar (July 15, 2013), Faculty of Pharmacy, Alexandria Univ.
Mai Mostafa Helmy (September 14, 2009), Faculty of Pharmacy, Alexandria Univ.
Sahar Mohamed Azmy El-Gowilly (September 13, 2004), Faculty of Pharmacy, Alexandria Univ.
Amal Galal Omar (May 13, 2002), Faculty of Pharmacy, Alexandria Univ.
MSc degrees
Yasser Habib Ezzat (May 4, 2021), Faculty of Pharmacy, Pharos University in Alexandria
Shrouk Sherif Kotb Elzokm (Jan 25, 2020), Faculty of Pharmacy, Alexandria Univ.
Mohammed Abdalla El-Lakany (Aug 27, 2019), Faculty of Pharmacy, Alexandria Univ.
Abdalla Moursi Wedn (Aug 27, 2019), Faculty of Pharmacy, Alexandria Univ.
Mahmoud Elsaid Ahmed Youssef (March 17, 2018), Faculty of Pharmacy, Suez Canal Univ.
Karim Samy Ibrahim (Feb 7, 2017), Faculty of Pharmacy, Alexandria Univ.
Marwa Youssef Sallam (December 26, 2015), Faculty of Pharmacy, Alexandria Univ.
Lamia Khiery Elsalakawy (June 16, 2014), Faculty of Pharmacy, Alexandria Univ.
Rabab Mohamed Ali (April 18, 2013), Faculty of Pharmacy, Alexandria Univ.
Mohamed Amin Fouda (December 16, 2010), Faculty of Pharmacy, Alexandria Univ.
Khaled Soliman Abd-Elrahman (November 9, 2009), Faculty of Pharmacy, Alexandria Univ.
Osama Fathalla Harraz (November 9, 2009), Faculty of Pharmacy, Alexandria Univ.
Eman yousry Gohar (June 9, 2008), Faculty of Pharmacy, Alexandria Univ.
Hanan Mohamed Samir El-Gowelli (March 10, 1997), Faculty of Pharmacy, Alexandria Univ.
Amal Galal Omar; September 11, May 30, 1996), Faculty of Pharmacy, Alexandria Univ.
Membership of Pharmacology Theses’ Examination Committees (29 PhD, 23 MSc)
PhD degrees
Bashaier Jassim Al-Zaid (Convener, October 11, 2023), Faculty of Medicine, Kuwait Univ.
Neha Munawar (Convener, October 9, 2023), Faculty of Medicine, Kuwait Univ.
Dina Mostafa Jragh (Convener, September 6, 2023), Faculty of Medicine, Kuwait Univ.
Nora Osama Abdel Rasheed (October 29, 2018), Faculty of Pharmacy, Cairo Univ.
Shimaa Mohamed Azmy Mohamed (September 1, 2018), Faculty of Pharmacy, Cairo Univ.
Noura Ahmed Mohamed Hassan (June 27, 2018), Faculty of Pharmacy, Zagazig Univ.
Aya Yahia Kamel Gawish (June 25, 2018), Faculty of Pharmacy, Port Said Univ.
Mostafa Adel Mohamed Rabie (May 5, 2018), Faculty of Pharmacy, Cairo Univ.
Mohamed Samir Abdel-Maksoud Megahed (March 17, 2018), Faculty of Pharmacy, Suez Canal Univ.
Nesrine Saeid Ibrahim El-Mezayen (March 3, 2018), Faculty of Pharmacy, Cairo Univ.
Safaa Hisham Hammoud (November 16, 2017), Faculty of Pharmacy, Beirut Arab Univ., Lebanon
Hanaa Khalaf Bayoumi Motawea (April 1, 2017), Faculty of Pharmacy, Helwan Univ.
Ebaa Mohamed Abd El-Monam Ali (November 14, 2015), Faculty of Pharmacy, Zagazig Univ.
Mennatallah Ahmed Ismail Ali (October 24, 2015), Faculty of Pharmacy, Cairo Univ.
Lamia Said Kandil (Sep 13, 2015), Institute of Graduate Studies and Research, Alexandria Univ.
Heba Karam Mohamed (June 15, 2015), Faculty of Pharmacy, Cairo Univ.
Shameem Hassan Abd El-Aziz Hassan (Jan 19, 2015), Faculty of Pharmacy, Helwan Univ.
Suzanne Aunni Naser (June 19, 2014), Faculty of Pharmacy, Beirut Arab Univ., Lebanon
Mohamed Amin Fouda (April 19, 2014), Faculty of Pharmacy, Alexandria Univ.
Eman yousry Gohar (June 19, 2013), Faculty of Pharmacy, Alexandria Univ.
Asmaa Fathi Galal (March 2, 2013), Faculty of Pharmacy, Cairo Univ.
Walaa Mohammed Adel El-Sabbagh (June 24, 2012), Faculty of Pharmacy, Cairo Univ.
Badr Mostafa Sadek Ibrahim (February 10, 2011), Faculty of Pharmacy, El-Mania Univ.
Mohammed Fathy Fadl El-Shafie (December 23, 2010), Faculty of Pharmacy, Al-Azhar Univ.
Marwa El-Said Ahmed El-Shamarka (November 25, 2010), National Research Center, Cairo.
Maha Ali Eissa Ahmed (April 21, 2010), Faculty of Pharmacy, Cairo University.
Mai Mostafa Helmy (August 20, 2009), Faculty of Pharmacy, Alexandria Univ.
Marwa Mohamed Safar (April 29, 2009), Faculty of Medicine, Alexandria Univ.
Dalia Kamal Mostafa (April 15, 2009), Faculty of Pharmacy, Cairo Univ.
Master degrees
Shrouk Sherif Kotb Elzokm (Jan 25, 2020), Faculty of Pharmacy, Alexandria Univ.
Mohammed Abdalla El-Lakany (Aug 27, 2019), Faculty of Pharmacy, Alexandria Univ.
Abdalla Moursi Wedn (Aug 27, 2019), Faculty of Pharmacy, Alexandria Univ.
Mohammed Abdel-Wahid El-Khatib (Aug 12, 2018), Faculty of Pharmacy, Alexandria Univ.
Mohamed Samir Abdel-Maksoud Megahed (April 19, 2018), Faculty of Science, Alexandria Univ.
Mahmoud Elsaid Ahmed Youssef (March 17, 2018), Faculty of Pharmacy, Suez Canal Univ.
Karim Samy Ibrahim (Feb 7, 2017), Faculty of Pharmacy, Alexandria Univ.
Nagwa Ismail Abd El-Hamid (November 27, 2016), Faculty of Pharmacy, Suez Canal Univ.
Esraa Saeed Shaban Habiba (April 23, 2016), Faculty of Medicine, Alexandria Univ.
Marwa Youssef Sallam (November 30, 2015), Faculty of Pharmacy, Alexandria Univ.
Ahmed Mohamed Darwesh Essa (October 25, 2015), Faculty of Pharmacy, Suez Canal Univ.
Sarah El-Sayed Mohamed (June 15, 2015), Faculty of Pharmacy, Cairo Univ.
Reham Hassan Mohammed Salim (November 13, 2014), Faculty of Pharmacy, Zagazig Univ.
Lamia Khiery Elsalakawy (June 1, 2014), Faculty of Pharmacy, Alexandria Univ.
Rabab Mohamed Ali (April 2, 2013), Faculty of Pharmacy, Alexandria Univ.
Omar Abd-El-Aziz Hamed (Dec 27, 2012), Medical Research Institute, Alexandria Univ.
Marwa Bakir Mohamed Bakir (May 24, 2011), Faculty of Pharmacy, Alexandria Univ.
Mohamed Amin Fouda (December 5, 2010), Faculty of Pharmacy, Alexandria Univ.
Khaled Soliman Abd-Elrahman (November 5, 2009), Faculty of Pharmacy, Alexandria Univ.
Osama Fathalla Harraz (October 29, 2009), Faculty of Pharmacy, Alexandria Univ.
Nour Mohamed Adel (October 21, 2009), Faculty of Pharmacy, Alexandria Univ.
Eman yousry Gohar (May 30, 2008), Faculty of Pharmacy, Alexandria Univ.
Eman Saleh Abd El-Aziz (May 28, 2008), Faculty of Pharmacy, Zagazig Univ.
Trainee awards
Amany E. El-Naggar, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology Conference, April 2-5, 2022.
Salwa A. Abuiessa, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology Conference, April 2-5, 2022.
Hagar A. Morgaan, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology Conference, April 2-5, 2022.
Abdalla M. Wedn, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Virtual Experimental Biology Conference, April 27-30, 2021.
Salwa A. Abuiessa, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Virtual Experimental Biology Conference, April 27-30, 2021.
Hagar A. Morgaan, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Virtual Experimental Biology Conference, April 27-30, 2021.
Marwa Y. Sallam, International Travel Award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology meeting, April 2020, San Diego, California, USA.
Salwa A. Abuiessa, International Travel Award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology meeting, April 2020, San Diego, California, USA.
Salwa A. Abuiessa, the “JPET Highlighted Trainee Author", for her first authorship on a manuscript titled "Preeclamptic fetal programming alters neuroinflammatory and cardiovascular consequences of endotoxemia in sex specific manners" https://www.ncbi.nlm.nih.gov/pubmed/32094295.
Abdalla A. Wedn, International travel award from American College of Toxicology (ACT) to participate in the 40th annual meeting of American Collage of Toxicology, Phoenix, Arizona, USA, November 2019.
Abdalla A. Wedn, International travel award from American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology Conference, Orlando, Florida, USA, April 2019.
Abdalla A. Wedn, Travel grant from Asian Counsel of Science (ACS) for oral presentation at Asian Conference on Science, Technology and Medicine (ACSTM), Dubai, UAE, February 2019.
Mohamed A El-Lakany, International speaker award (oral presentation) from the American Society for Pharmacology and Experimental Therapeutics (ASPET) to participate in the Experimental Biology Conference, Orlando, Florida, USA, April 2019.
Mohamed A El-Lakany, Best oral presentation at the Faculty of Pharmacy Annual Scientific Conference, Alexandria University, Egypt, September 2019.
Mohamed A El-Lakany, International travel award from Alexandria University, Egypt, to participate in the Experimental Biology Conference, San Diego, California, USA, EB2018.
International Conferences, Workshops (42)
American Society for Pharmacology and Experimental Therapeutic meeting, St. Louis, Missouri, U.S.A (May 18-21, 2023).
Experimental Biology Meeting, Philadelphia, Pennsylvania, U.S.A (April 2-5, 2022).
International conference on Pharmaceutical & Health Sciences, Alexandria university, Alexandria, Egypt (Nov 6-7, 2019).
The annual Pharmacology Department Conference, Faculty of Pharmacy, Zagazig Univ., Egypt (Feb 11, 2019).
2nd International pharmaceutical Conference, Ain Shams University, Cairo, Egypt (Nov 13-15, 2018).
Third International Conference “Towards Best Pharmacy Practices: Enhancing Pharmacy Education”, Faculty of Pharmacy, Beirut Arab Univ., Lebanon (May 8-9, 2018).
Experimental Biology Meeting, Chicago, Illinois, U.S.A (April 22-26, 2017).
7th Euro-Global Summit on Toxicology and Applied Pharmacology, Rome, Italy (Oct 24-26, 2016).
Experimental Biology Meeting, San Diego, California, U.S.A (April 2-6, 2016).
International Conference on “Advances in Pharmaceutical Sciences”, Pharos Univ., Alexandria, Egypt (Oct 27-29, 2015
Workshop: Recent Concepts on Cardiovascular Complications, Faculty of Pharmacy, King Abdelaziz University, Saudi Arabia (May 19-20, 2015)
3rd Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt (Feb 9-11, 2015).
Egyptian Society for Pharmacology and Experimental Therapeutics, Cairo, Egypt (Dec 20, 2014).
The 6th International Conference on Natural Toxins, Suez Canal University, Ismailia, Egypt (Dec 15-16, 2014).
Experimental Biology Meeting, San Diego, California, U.S.A (April 26-30, 2014).
Experimental Biology Meeting, Boston, U.S.A (April 20-24, 2013).
Egyptian Society for Pharmacology and Experimental Therapeutics, British Univ. in Egypt, Cairo (April 2013).
International Conference on Advanced Basic and Applied Sciences, Hurghada, Egypt (Nov 6-9, 2012).
Experimental Biology Meeting, San Diego, California, U.S.A (April 21-25, 2012).
Experimental Biology Meeting, Washington DC, U.S.A. (April 9-13, 2011).
Workshop: Patient Safety (Risk Management), Medical Research Institute, Alexandria, Egypt (Feb 27-28, 2011).
International Pharmaceutical Conference, Faculty of Pharmacy, Beirut Arab Univ., Lebanon (May 6-7, 2010).
Experimental Biology Meeting, Anaheim, California, U.S.A (April 24-28, 2010).
Neuroscience Symposium, East Carolina Univ. Chapter of the Society for Neuroscience, USA. (Nov 2008).
Experimental Biology Meeting, San Diego, California, U.S.A (April 2008).
BioVision Alexandria, Alexandria, Egypt (April 2006).
Workshop: The Scientific use of informatics, Faculty of Pharmacy, Alexandria University (Feb 21-24, 2005).
Experimental Biology Meeting, Washington DC, U.S.A. (April 2004).
Experimental Biology Meeting, San Diego, California, U.S.A (April 2003).
Genetic Engineering Workshop, Institute of Graduate Studies & Research, Alexandria, Egypt (February 2000).
Egyptian Society of Toxicology, Alexandria, Egypt (October 1999).
Experimental Biology Meeting, Washington DC, U.S.A (April 1999).
American Heart Association, Dallas, Texas, U.S.A. (November 1998).
Experimental Biology Meeting, San Francisco, California, U.S.A. (April 1998).
Experimental Biology Meeting, New Orleans, Louisiana, U.S.A. (April 1997).
In Situ Polymerase Chain Reaction Symposium, Research Triangle Park, North Caroline, U.S.A. (March 1996).
Egyptian Society for Pharmacology and Experimental Therapeutics, Cairo, Egypt (February 1994).
American Society for Pharmacology and Experimental Therapeutics, Orlando, Florida, U.S.A. (August 1992).
British Pharmacological Society, London, U.K. (January 1990).
British Pharmacological Society, Leeds, U.K. (July 1989)
British Pharmacological Society, Nottingham, U.K. (September 1988).
Egyptian Society for Pharmacology and Experimental Therapeutics, Alexandria, Egypt (March 1985).
Chaired Conference Sessions
International conference on Pharmaceutical & Health Sciences, Alexandria, Egypt (Nov 6-7, 2019).
2nd International pharmaceutical Conference, Ain Shams University, Cairo, Egypt (Nov 13-15, 2018).
7th Euro-Global Summit on Toxicology and Applied Pharmacology, Rome, Italy (Oct 24-26, 2016).
International Conference on “Advances in Pharmaceutical Sciences”, Pharos Univ., Alexandria, Egypt (Oct 27-29, 2015).
Egyptian Society for Pharmacology and Experimental Therapeutics, British Univ. in Egypt, Cairo (Dec 2014).
Egyptian Society for Pharmacology and Experimental Therapeutics, British Univ. in Egypt, Cairo (April 2013).
International Conference on Advanced Basic and Applied Sciences, Hurghada, Egypt (Nov 6-9, 2012).
Membership In Conference Program Technical Committees
Scientific Committee, 1st Healthcare and Sport Congress, 9-10 Nov, 2023, Bahrain.
Organizing Committee, 5th International conference on Pharmaceutical Sciences (ICPS 2016, Aug 10-11, Dubai, U.A.E.).
Organizing Committee, 4th ScienceOne International Conference on Environmental Sciences (ICES 2015, Jan 21-23, Dubai, U.A.E.).
Organizing Committee, 3rd ScienceOne Conference on Drug Discovery and Development (SCDDD 2014, Jan 21-23, Dubai, U.A.E.).
Invited oral presentations (Keynote speaker)
“Central cholinergic modulation of neuroinflammatory and cardiac autonomic neuropathic effects of endotoxemia”, Faculty of Medicine, Kuwait University (Jan 17, 2021)
“Highlights of hypertensive and vasculotoxic effects of cyclosporine”, International conference on Pharmaceutical & Health Sciences, Alexandria, Egypt (Nov 6-7, 2019).
“Four Decades of global cyclosporine-hypertension research”, the annual Pharmacology Department Conference, Faculty of Pharmacy, Zagazig Univ., Egypt (Feb 11, 2019)
“Central and peripheral mechanisms of cyclosporine-induced hypertension”, Department of Pharmacy, University of Pisa, Italy (July 4, 2018).
“Endothelin modulation of the cyclosporine/NSAIDs cardiovascular and renal interactions”, 7th Euro-Global Summit on Toxicology and Applied Pharmacology, Rome, Italy (Oct 24-26, 2016).
“Sexual dimorphism in nicotine interaction with baroreflex control of heart rate”, Experimental Biology meeting, San Diego, California, U.S.A (April 2-6, 2016).
“Nicotine negatively impacts cardiac autonomic control and reflexes”, Faculty of Pharmacy, King Abdelaziz University, Saudi Arabia (May 19-20, 2015)
“Sympathetic/endothelin modulation of cyclosporine hypertension”, Faculty of Pharmacy, King Abdelaziz University, Saudi Arabia (May 19-20, 2015).
“Peripheral and central mechanisms of cyclosporine-induced hypertension”, 3rd Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt (Feb 9-11, 2015).
“Divergent estrogenic modulation of the nicotine-baroreflex interaction”, the 6th International Conference on Natural Toxins, Suez Canal University, Ismailia, Egypt (Dec 15-16, 2014).
“Gender and hormonal specificities of the nicotine interaction with cardiac reflexes”, International Conference on Advanced Basic and Applied Sciences, Beni-Suef University, Hurghada, Egypt (Nov 2012).
"Cyclosporine-induced hypertension: mechanisms and management", Keynote Speaker, International Pharmaceutical Conference, Bierut Arab Univ., Faculty of Pharmacy, Lebanon (May 2010).
“Writing a scientific paper”, Pharmacy, Alexandria Univ., Egypt (Feb 2008).
“Diagnostic Tools for Cardiovascular Abnormalities”, Faculty of Pharmacy, Pharos Univ., Alexandria, Egypt (July 2007).
“Tobacco smoking, an overview”, Faculty of Pharmacy, Alexandria University, Egypt (Mar 2002).
"Role of NMDA and non-NMDA receptors in ethanol-baroreflex interaction”, Faculty of Pharmacy, Kuwait Univ., Kuwait (Oct 1998).
"Central mechanisms of ethanol-induced attenuation of arterial baroreflexes”, School of Medicine, East Carolina Univ., NC, USA (Oct 1997).
"Interaction of ethanol with arterial baroreceptor function”, School of Medicine, East Carolina Univ., NC, USA (Nov 1992).
Cardiorenal aberrations caused by inflammatory disorders such as sepsis and preeclampsia. We are interested in understanding cellular and molecular underpinnings of pathophysiology, pharmacotherapy, peripheral and central modulation, sexual dimorphism, and gonadal hormone regulation of these pathologies.
(A) Patent
Patent No: US 10,653,666 B1
Issued by: United States Patent and Trademark Office
Application No: 16/41,826
Filed: Jan 14, 2020
Date of Patent: May 19, 2020
Title: Cardioprotective nano-pharmaceutical formulation
Inventors: Usama A. Fahmy, Noura A. Hassan, Ahmad S. Azhar, Mahmoud M. El-Mas, Hany El-Bassossy.
Assignee: King Abdulaziz University, Jeddah, Saudie Arabia.
(B) Invited book chapters
El-Lakany MA, Wedn AM, El-Mas MM (2024). Role of Oxidative Stress and Interrelated Cellular Offences in Sex Modulation of Cardiorenal Sequels of Sepsis. In: Eid AH, Kobeissy F, El-Yazbi AF (eds) Oxidative Stress in Cardiovascular-Metabolic Diseases. Oxidative Stress in Applied Basic Research and Clinical Practice, Aug 4, pp. 227-295, Springer, Cham. Print ISBN978-3-031-62130-7, Online ISBN978-3-031-62131-4. doi.org/10.1007/978-3-031-62131-4_9
El-Mas MM, Abdel-Rahman AA (2019). Role of alcohol oxidative metabolism in its cardiovascular and autonomic effects. In: Ren J, Zhang Y, Ge J (eds) Aldehyde Dehydrogenases, Advances in Experimental Medicine and Biology, July 31, vol. 1193, pp. 1-33, Springer, Singapore. Print ISBN 978-981-13-6259-0, Online ISBN 978-981-13-6260-6. doi: 10.1007/978-981-13-6260-6_1.
(C) Full-length research papers (166)
Abdelhady SA, Abuiessa SA, Elhamammy RH, El-Deeb NM, El-Mas MM (2024). Hepatoprotective effect of prenatal celecoxib in weaning preeclamptic rats: Role of HMGB1/MAPKs signaling. Eur J Pharmacol Sep 5;978:176769. doi: 10.1016/j.ejphar.2024.176769.
Serageldin MA, El-Bassiouny NA, El-Kerm Y, Aly RG, Helmy MW, El-Mas MM, Kassem AB (2024). A randomized controlled trial of neoadjuvant metformin with chemotherapy in non-diabetic breast cancer women: The METNEO study. Br J Clin Pharmacol Aug 7, doi: org/10.1111/bcp.16193.
Abuiessa SA, Helmy MM, El-Gowilly SM, El-Mas MM (2024). Gestationally administered RAS modulators reprogram endotoxic cardiovascular and inflammatory profiles in adult male offspring of preeclamptic rats. Naunyn-Schmiedeberg's Arch of Pharmacol July 24. doi: 10.1007/s00210-024-03305-2.
El-Naggar AE, Helmy MM, El-Gowilly SM, El-Mas MM (2024). Suppression by central adenosine A3 receptors of the cholinergic defense against cardiovascular aberrations of sepsis: Role of PI3K/MAPKs/NFκB signaling. Front Pharmacol Jun 20;15:1418981. doi: 10.3389/fphar.2024.1418981.
Ayieng’a EO, Afify EA, Abuiessa SA, Elblehi SS, El-Gowilly SM, El-Mas MM (2023). Morphine aggravates inflammatory, behavioral, and hippocampal structural deficits in septic rats. Sci Rep Dec 5, 13(1):21460. doi: 10.1038/s41598-023-46427-y.
El-Naggar AE, Helmy MM, El-Gowilly SM, El-Mas MM (2023). Adenosine A1 receptors of the medullary solitary tract arbitrate the nicotine counteraction of neuroinflammation and cardiovascular dysfunction in septic rats. Sci Rep Oct 19;13(1):17818. doi.org/10.1038/s41598-023-4.
Abdelhady SA, Ali MA, Yacout DM, Essawy MW, Kandil LS, El-Mas MM (2023). The suppression of MAPK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats. Sci Rep Oct 15;13(1):17498. doi: 10.1038/s41598-023-44617-2.
Khalifa AA, Ali MA, El-Sokkary NH, Elblehi SS, El-Mas MM (2023). Mitochondrial modulation of amplified preconditioning influences of remote ischemia plus erythropoietin against skeletal ischemia/reperfusion injury in rats. Life Sci. Sep 15;329:121979. doi: 10.1016/j.lfs.2023.121979.
Morgaan HA, Sallam MY, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2023), Preeclamptic programming unevenly perturbs inflammatory and renal vasodilatory outcomes of endotoxemia in rat offspring: modulation by losartan and pioglitazone. Front Pharmacol Apr 25; 14:1140020. doi: 10.3389/fphar.2023.1140020.
Serageldin MA, Kassem AB, El-Kerm Y, Helmy MW, El-Mas MM, El-Bassiouny NA (2023). The effect of metformin on chemotherapy-induced toxicities in non-diabetic breast cancer patients: A randomized controlled study. Drug Safety, Jun, 46(6): 587-599. doi: 10.1007/s40264-023-01305-4.
Morgaan HA, Sallam MY, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2023). The renin-angiotensin system modulates endotoxic postconditioning of exacerbated renal vasoconstriction in preeclamptic offspring. Sci Rep. Jan 17;13(1):881. doi: 10.1038/s41598-023-27923-7.
Ali MA, Abdelhady SA, Yacout DM, Kandil LS, Elblehi SS, El-Mas MM (2022). Gestational NSAIDs distinctly reprogram cardiac injury in preeclamptic rats: roles of cyclooxygenase, apoptotic and autophagic trails. Life Sci. Dec 1;310:121130. doi: 10.1016/j.lfs.2022.121130.
Abuiessa SA, Helmy MM, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2022). Dysregulated ACE/Ang II/Ang1-7 signaling provokes cardiovascular and inflammatory sequelae of endotoxemia in weaning preeclamptic rats. Eur J Pharmacol. Dec 5;936:175344. doi: 10.1016/j.ejphar.2022.175344.
Sallam MY, El-Gowilly SM, El-Mas MM (2022). Central α7 and α4β2 nicotinic acetylcholine receptors offset arterial baroreceptor dysfunction in endotoxic rats. Naunyn-Schmiedeberg's Arch of Pharmacol Dec, 395, 1587–1598. doi: 10.1007/s00210-022-02289-1.
Abuiessa SA, El-Gowilly SM, El-Gowelli HM, Helmy MM, El-Mas MM (2021). Short-lived sensitization of cardiovascular outcomes of postpartum endotoxemia in preeclamptic rats: role of medullary solitary tract neuroinflammation. Eur J Pharmacol, Nov 5, 910, 174494.
Habib YH, Gowayed MA, Abdelhady SA, El-Deeb NM, Inas E. Darwish IE, El-Mas MM (2021). Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats. Naunyn Schmiedebergs Arch Pharmacol. Nov;394(11):2273-2287. doi: 10.1007/s00210-021-02146-7.
Abdelhady SA, Ali MA, Al-Shafie TA, Abdelmawgoud EM, Yacout DM, El-Mas MM (2021). Montelukast potentiates the anti-inflammatory effect of NSAIDs in the rat paw formalin model and simultaneously minimizes the risk of gastric damage. Inflamm Res. Sep;70(9):981-992. doi: 10.1007/s00011-021-01492-9.
Wedn AM, El-Bassossy HM, Eid AH, El-Mas MM (2021). Modulation of preeclampsia by the cholinergic anti-inflammatory pathway: therapeutic perspectives. Biochem Pharmacol. Oct;192:114703. doi: 10.1016/j.bcp.2021.114703.
Ahmed OA, Hassan NA, Azhar AS, El-Mas MM, El-Bassossy HM (2021). A nano-pharmaceutical formula of quercetin protects from cardiovascular complications associated with metabolic syndrome. Front Pharmacol. Aug 11;12:696981. doi: 10.3389/fphar.2021.696981.
Elzokm SS, Fouda MA, Abdel Moneim RA, El-Mas MM (2021). Distinct effects of calcineurin dependent and independent immunosuppressants on endotoxemia-induced nephrotoxicity in rats: role of androgens. Clin Exp Pharmacol Physiol. Sep;48(9):1261-1270. doi: 10.1111/1440-1681.13526.
Habib YH, Abdelhady SA, Gowayed MA, El-Deeb NM, Inas E. Darwish IE, El-Mas MM (2021). Prenatal endothelin or thromboxane receptor antagonism surpasses sympathoinhibition in improving cardiorenal malfunctions in preeclamptic rats. Toxicol Appl Pharmacol. Sep 1;426:115615. doi: 10.1016/j.taap.2021.115615.
Sallam MY, El-Gowilly SM, El-Mas MM (2021). Cardiac and brainstem neuroinflammatory pathways account for androgenic incitement of cardiovascular and autonomic manifestations in endotoxic male rats. J Cardiovasc Pharmacol, May 1;77(5):632-641.
Youssef ME, El-Mas MM, Abdelrazek HM, El-Azab MF (2021). α7-nAChRs-mediated therapeutic angiogenesis accounts for the advantageous effect of low nicotine doses against myocardial infarction in rats. Eur J Pharmacol, Mar 5, 898, 173996.
Nasser SA, Afify EA, Kobeissy F, Hamam B, Eid AH, El-Mas MM (2021). Inflammatory basis of atherosclerosis: modulation by sex hormones. Curr Pharm Des, 27(18), 2099–2111. doi: 10.2174/1381612827666210122142811.
Sallam MY, El-Gowilly SM, El-Mas MM (2021). Androgenic modulation of arterial baroreceptor dysfunction and neuroinflammation in endotoxic male rats. Brain Res. Apr 1, 1756, 147330.
El-Lakany MA, El-Gowelli HM, Fouda MA, Sallam MY, El-Mas MM (2020). Nicotine uncovers endotoxic-like cardiovascular manifestations in female rats: estrogen and nitric oxide dependency. Tox Lett, Dec 15;335:28-36.
Abuiessa SA, Wedn AM, El-Gowilly SM, Helmy MM, El-Mas MM (2020). Preeclamptic fetal programming alters neuroinflammatory and cardiovascular consequences of endotoxemia in sex specific manners. J Pharmacol Exp Ther, May;373(2):325-336.
Ahmed OA, El-Bassossy H, Azhar AS, Tarkhan MM, El-Mas MM (2020). Interference with AGEs formation and AGEs-induced vascular injury mediates curcumin vascular protection in metabolic syndrome. Sci Rep, 10 (1), 315.
Wedn AM, El-Gowilly SM, El-Mas MM (2020). The α7-nAChR/heme oxygenase-1/carbon monoxide pathway mediates the nicotine counteraction of renal inflammation and vasoconstrictor hyporeactivity in endotoxic male rats. Inflamm Res 69, 217–231.
Wedn AM, El-Gowilly SM, El-Mas MM (2020). Time and sex dependency of hemodynamic, renal, and survivability effects of endotoxemia in rats. Saudi Pharm J 28, 127–135.
El-Mas MM, Abdel-Rahman AA (2019). Role of Alcohol Oxidative Metabolism in Its Cardiovascular and Autonomic Effects. Adv Exp Med Biol 1193:1-33.
Wedn AM, El-Gowilly SM, El-Mas MM (2019). Nicotine reverses the enhanced renal vasodilator capacity in endotoxic rats: role of α7/α4β2 nAChRs and HSP70. Pharmacol Rep 71, 782–793.
Sallam MY, El-Gowilly SM, Fouda MA, Abd-Alhaseeb MA, El-Mas MM (2019). Brainstem cholinergic pathways diminish cardiovascular and neuroinflammatory actions of endotoxemia in rats: Role of NFκB/α7/α4β2AChRs signaling. Neuropharmacology 157, 107683.
Helmy MM, Helmy MW, El-Mas MM (2019). Upregulation of cystathionine-γ-lyase/hydrogen sulfide pathway underlies the celecoxib counteraction of cyclosporine-induced hypertension and renal insult in rats. Prostaglandins Other Lipid Mediat 141, 1-10.
Hammoud SH, Alkhansa S, Mahjoub N, Omar AG, El-Mas MM, Eid AA (2018). Molecular basis of the counteraction by calcium channel blockers of cyclosporine nephrotoxicity. Am J Physiol Renal Physiol. 315(3):F572-F582.
Sallam MY, El-Gowilly SM, Abdel-Galil AA, El-Mas MM (2018). Activation of central GABAB receptors offsets the cyclosporine counteraction of endotoxic cardiovascular outcomes in conscious rats. Fundam Clin Pharmacol 32, 485-498.
Sallam MY, El-Gowilly SM, El-Gowelli HM, El-Lakany M, El-Mas MM (2018). Additive counteraction by α7 and α4β2 nAChRs of the hypotension and cardiac sympathovagal imbalance evoked by endotoxemia in male rats. Eur J Pharmacol, 834, 36–44.
Fouda MA, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2018). Hemin blunts the depressant effect of chronic nicotine on reflex tachycardia via activation of central NOS/PI3K pathway in female rats. Pharmacol Rep 70, 455–462.
Helmy MW, Helmy MM, El-Mas MM (2018). Enhanced lipoxygenase/LTD4 signaling accounts for the exaggerated hypertensive and nephrotoxic effects of cyclosporine plus indomethacin in rats. Biomed Pharmacother 102, 309-316.
Ibrahim KS, El-Yazbi AF, El-Gowelli HM, El-Mas MM (2018). Heme oxygenase byproducts variably influences myocardial and autonomic dysfunctions induced by the cyclosporine/diclofenac regimen in female rats. Biomed Pharmacother 101, 889-897.
El-Yazbi AF, Eid AH, El-Mas MM (2018). Cardiovascular and renal interactions between cyclosporine and NSAIDs: Underlying mechanisms and clinical relevance. Pharmacol Res 129, 251–261.
El-Lakany MA, Fouda MA, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2018). Gonadal hormone receptors underlie the resistance of female rats to inflammatory and cardiovascular complications of endotoxemia. Eur J Pharmacol 823 ,41-48.
El-Bassossy HM, Awan Z, El-Mas MM (2017). Perinatal ciclosporin A exposure elicits sex-related cardiac dysfunction and inflammation in the rat progeny, Toxicol Lett, 281, 35-43.
Hammoud SH, Omar AG, Eid AA, El-Mas MM (2017). CYP4A/CYP2C modulation of the interaction of calcium channel blockers with cyclosporine on EDHF-mediated renal vasodilations in rats. Toxicol Appl Pharmacol, 334, 110-119.
El-Gowelli HM, Ibrahim KS, El-Yazbi AF, El-Mas MM (2017). Role of NADPHox/Rho-kinase signaling in the cyclosporine-NSAIDs interactions on blood pressure and baroreflexes in female rats. Life Sci 185, 15-22.
Ibrahim KS, El-Yazbi AF, El-Gowelli HM, El-Mas MM (2017). Opposite modulatory effects of selective and non-selective cyclooxygenase inhibition on cardiovascular and autonomic consequences of cyclosporine in female rats. Basic Clin Pharmacol Toxicol 120, 571–581.
El-Yazbi AF, Ibrahim KS, El-Gowelli HM, El-Deeb NM, El-Mas MM (2017). Modulation by NADPH oxidase of the chronic cardiovascular and autonomic interaction between cyclosporine and NSAIDs in female rats. Eur J Pharmacol 806, 96–104.
El-Bassossy HM, Banjar ZM, El-Mas MM (2017). The inflammatory state provokes sexual dimorphism in left ventricular and electrocardiographic effects of chronic cyclosporine in rats. Sci Rep 7, 42457.
Sallam MY, El-Gowilly SM, Abdel-Galil AA, El-Mas MM (2017). Cyclosporine counteracts endotoxemia-evoked reductions in blood pressure and cardiac autonomic dysfunction via central sGC/MAPKs signaling in rats. Eur J Pharmacol 797, 143-152.
Nasser SA, Sabra R, Elmallah AI, Khedr MM, Mohy El-Din MM, El-Mas MM (2016). Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: role of arterial baroreflexes and vasoreactivity. Life Sci 163, 1-10.
Sallam MY, El-Gowilly SM, Abdel-Galil AA, El-Mas MM (2016). Modulation by central MAPKs/PI3K/sGc of the TNFα/iNOS-dependent hypotension and compromised cardiac autonomic control in endotoxic rats. J Cardiovasc Pharmacol 68, 171-181.
Sallam MY, El-Gowilly SM, Abdel-Galil AA, El-Mas MM (2016). Central GABAA receptors are involved in inflammatory and cardiovascular consequences of endotoxemia in conscious rats. Naunyn-Schmiedeberg’s Arch Pharmacol 389, 279-288.
Fouda MA, El-Gowelli HM, El-Gowilly SM, El-Mas MM (2015). The estrogen-dependent baroreflex dysfunction caused by nicotine in female rats is mediated via NOS/HO inhibition: role of sGC/PI3K/MAPKERK. Toxicol Appl Pharmacol 289, 466–473.
Helmy MM, Helmy MW, El-Mas MM (2015). Additive renoprotection by pioglitazone and fenofibrate against inflammatory, oxidative and apoptotic manifestations of cisplatin nephrotoxicity: Modulation by PPARs. PLoS One, 10(11): e0142303.
Fan M, El-Mas MM, Abdel-Rahman AA (2015). Preserved left ventricular performance in spontaneously hypertensive rats following preload and afterload challenges. J Hypertens Manag 1:1.
El-Mas MM, Abdel-Rahman AA (2015). Estrogen modulation of the ethanol-evoked myocardial oxidative stress and dysfunction via DAPK3/Akt/ERK activation in male rats. Toxicol Appl Pharmacol 287, 284-292.
Helmy MW, El-Gowelli HM, Ali RM, El-Mas MM (2015). Endothelin ETA receptor/lipid peroxides/COX-2/TGF-β1 signaling underlies aggravated nephrotoxicity caused by cyclosporine plus indomethacin in rats. Br J Pharmacol 172, 4291–4302.
El-Mas MM, Helmy MW, Ali RM, El-Gowelli HM (2015). Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling. Toxicol Appl Pharmacol 284, 1-7.
El-Gowelli HM, El-Mas MM (2015). Central modulation of cyclosporine-induced hypertension. Naunyn-Schmiedeberg’s Arch Pharmacol 388, 351-361.
El-Mas MM, El-gowilly SM, Elsalakawy LK, El-Gowelli HM (2014). Estrogen compromises the facilitatory effect of chronic nicotine on adenosine A2B receptor/K+ channel-mediated renal vasodilations. Clin Exp Pharmacol Physiol 41, 600–607.
El-Mas MM, Abdel-Rahman AA (2014). Ser/thr phosphatases tonically attenuate the ERK-dependent pressor effect of ethanol in the rostral ventrolateral medulla in normotensive rats. Brain Res 1577, 21-28.
Fouda MA, El-Gowelli HM, El-Gowilly SM, Rashed L, El-Mas MM (2014). Impairment of nitric oxide synthase but not heme oxygenase accounts for baroreflex dysfunction caused by chronic nicotine in female rats. PLoS One 9 (5), e98681.
Nasser SA, El-Mas MM (2014). Endothelin ETA receptor antagonism in cardiovascular disease. Eur J Pharmacol 737, 210-213.
Gohar EY, El-Gowilly SM, El-Gowelli HM, El-Demellawy MA, El-Mas MM (2014). PI3K/Akt-independent NOS/HO activation accounts for the facilitatory effect of nicotine on acetylcholine renal vasodilations: modulation by ovarian hormones. PLoS One 9(4): e95079.
El-Mas MM, Abdel-Rahman AA (2014). Nongenomic effects of estrogen mediate the dose-related myocardial oxidative stress and dysfunction caused by acute ethanol in female rats. Am J Physiol Endocrinol Metab 306, E740-747.
El-Mas MM, Abdel-Rahman AA (2014). Endothelial and neuronal nitric oxide synthases variably modulate the estrogen-mediated control of blood pressure and cardiovascular autonomic control. Clin Exp Pharmacol Physiol 41, 246-254.
El-Gowelli HM, Helmy MW, Ali RM, El-Mas MM (2014). Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ETB receptor cascade. Toxicol Appl Pharmacol 275, 88-95.
Nasser SA, Elmallah AI, Sabra R, Khedr MM, Mohy El-Din MM, El-Mas MM (2014). Blockade of endothelin ETA, but not thromboxane, receptors offsets the cyclosporine-evoked hypertension and interrelated baroreflex and vascular dysfunctions. Eur J Pharmacol 727, 52-59.
El-Mas MM, Fan M, Abdel-Rahman AA (2013). Role of rostral ventrolateral medullary ERK/JNK/p38 MAPK signaling in the pressor effects of ethanol and its oxidative product acetaldehyde. Alcohol Clin Exp Res 37, 1827–1837.
El-Mas MM, El-Gowelli HM, Michel MC (2013). Publication trends in Naunyn-Schmiedeberg’s Archives of Pharmacology: focus on pharmacology in Egypt. Naunyn-Schmiedebergs Arch Pharmacol 386, 929-933.
El-Mas MM, Abdel-Rahman AA (2013). Cardiovascular autonomic modulation by nitric oxide synthases accounts for the augmented enalapril-evoked hypotension in ethanol-fed female rats. Alcohol 47, 339-346.
Gohar EY, El-gowilly SM, El-Gowelli HM, El-Mas MM (2013). Nicotine paradoxically affects the facilitatory effect of ovarian hormones on the adenosine receptor-mediated renal vasodilation. Eur J Pharmacol 710, 1-9.
El-Gowelli HM, El-gowilly SM, Elsalakawy LK, El-Mas MM (2013). Nitric oxide synthase/K+ channel cascade triggers the adenosine A2B receptor-sensitive renal vasodilation in female rats. Eur J Pharmacol 702, 116-125.
El-Mas MM, Fan M, Abdel-Rahman AA (2012). Differential modulation by vascular nitric oxide synthases of the ethanol-evoked hypotension and autonomic dysfunction in female rats. Alcohol 46, 727-735.
El-Mas MM, Mohy El-Din MM, Helmy MM, Omar AG (2012). Redox imbalances incite the hypertensive, baroreflex, and autonomic effects of cyclosporine in rats. Eur J Pharmacol 694, 82-88.
El-Mas MM, El-Gowelli HM, El-gowilly SM, Fouda MA, Helmy MM (2012). Estrogen provokes the depressant effect of chronic nicotine on vagally-mediated reflex chronotropism in female rats. J Pharmacol Exp Ther 342, 568-575.
Harraz OF, El-Gowelli HM, Mohy El-Din MM, Ghazal AM, El-Mas MM (2012). Adenosinergic modulation of the imidazoline I1-receptor-dependent hypotensive effect of ethanol in acute renal failure. Food Chem Toxicol 50, 2622-2628.
El-Mas MM, Abdel-Rahman AA (2012). Exacerbation of myocardial dysfunction and autonomic imbalance contribute to the estrogen-dependent chronic hypotensive effect of ethanol in female rats. Eur J Pharmacol 679, 95-100.
El-Mas MM, Abdel-Rahman AA (2012). Enhanced catabolism to acetaldehyde in rostral ventrolateral medullary neurons accounts for the pressor effect of ethanol in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol 302, H837-844.
El-Mas MM, Omar AG, Helmy MM, Mohy El-Din MM (2012). Crosstalk between central pathways of nitric oxide and carbon monoxide in the hypertensive action of cyclosporine. Neuropharmacology 62, 1890-1896.
El-Mas MM, Fouda MA, El-gowilly SM, Saad EI (2012). Central estrogenic pathways protect against the depressant action of acute nicotine on reflex tachycardia in female rats. Toxicol Appl Pharmacol 258, 410-417.
El-Gowelli HM, Abd-Elrahman KS, Saad EI, El-gowilly SM, Abdel-Galil AA, El-Mas MM (2011). PPARγ dependence of cyclosporine-isoprenaline renovascular interaction: Roles of nitric oxide synthase and heme oxygenase. J Cardiovasc Pharmacol 58, 173-180.
El-Mas MM, El-gowilly SM, Fouda MA, Saad EI (2011). Role of adenosine A2A receptor signaling in the nicotine-evoked attenuation of reflex cardiac sympathetic control. Toxicol Appl Pharmacol 254, 229-237.
El-Mas MM, El-Gowelli HM, Abd-Elrahman KS, Saad EI, Abdel-Galil AA, Abdel-Rahman AA (2011). Pioglitazone abrogates cyclosporine-evoked hypertension via rectifying abnormalities in vascular endothelial function. Biochem Pharmacol 81, 526–533.
El-Mas MM, Abdel-Rahman AA (2011). Bradykinin B2 receptor-dependent enhancement of enalapril-evoked hypotension in ethanol-fed female rats. J Cardiovasc Pharmacol 57, 72–78.
El-Mas MM, El-gowilly SM, Gohar EY, Ghazal AM, Abdel-Rahman AA (2011). Estrogen dependence of the renal vasodilatory effect of nicotine in rats: role of α7 nicotinic cholinergic receptor/eNOS signaling. Life Sci 88, 187-193.
El-Mas MM, Fan M, Abdel-Rahman AA (2011). Upregulation of cardiac NOS due to endotoxemia and vagal overactivity contribute to the hypotensive effect of chronic ethanol in female rats. Eur J Pharmacol 650, 317-323.
El-Mas MM, Abdel-Rahman AA (2010). Reduced cardiac contractile force due to sympathovagal dysfunction mediates the additive hypotensive effects of limited-access regimens of ethanol and clonidine in SHRs. J Pharmacol Exp Ther 335, 852-860.
Abd-Elrahman KS, El-Gowelli HM, Saad EI, Abdel-Galil AA, El-Mas MM (2010). Role of PPARγ/nitric oxide synthase signaling in the cyclosporine-induced attenuation of endothelium-dependent renovascular vasodilation. J Cardiovasc Pharmacol 56, 195-202.
Nasr MA, El-gowilly SM, El-Mas MM (2010). Comparable renovascular protective effects of moxonidine and Simvastatin in rats exposed to cigarette smoke. Vascul Pharmacol 53, 53–60.
El-Mas MM, El-Gowelli HA, Ghazal AM, Harraz OF, Mohy El-Din MM (2009). Facilitation of central imidazoline I1-site/extracellular signal-regulated kinase/p38 mitogen-activated protein kinase signalling mediates the hypotensive effect of ethanol in rats with acute renal failure. Br J Pharmacol 158, 1629-1640.
El-Mas MM, Abdel-Rahman AA (2009). Longitudinal assessment of the modulatory effect of estrogen on blood pressure and cardiac autonomic activity in female rats. Clin Exp Pharmacol Physiol 36, 1002–1009.
El-Mas MM, Fan M, Abdel-Rahman AA (2009). Facilitation of myocardial PI3K/Akt/nNOS signaling contributes to ethanol-evoked hypotension in female rats. Alcohol Clin Exp Res 33, 1158-1168.
El-Mas MM, El-gowilly SM, Gohar EY, Ghazal AM (2009). Sex and hormonal influences on the nicotine-induced attenuation of isoprenaline vasodilations in the rat perfused kidney. Can J Physiol Pharmacol 87, 539-548.
El-Mas MM, Omar AG, Helmy MM, Mohy El-Din MM (2009). Interruption of central neuronal pathway of imidazoline I1 receptor mediates the hypertensive effect of cyclosporine in rats. Brain Res 1248, 96-106.
El-Mas MM, Abdel-Rahman AA (2009). Chronic ethanol attenuates centrally-mediated hypotension elicited via α2-adrenergic, but not I1-imidazoline, receptor activation in female rats. Life Sci 84, 111-118.
El-Mas MM, El-gowilly SM, Gohar EY, Ghazal AM (2008). Pharmacological characterization of cellular mechanisms of the renal vasodilatory effect of nicotine in rats. Eur J Pharmacol 588, 294–300.
El-gowilly SM, Ghazal AM, Gohar EY, El-Mas MM (2008). Exacerbation by nicotine of the cyclosporine A-induced impairment of β-adrenoceptor-mediated renal vasodilation in rats. Clin Exp Pharmacol Physiol 35, 1164-1171.
El-Mas MM, Fan M, Abdel-Rahman AA (2008). Endotoxemia-mediated facilitation of cardiac iNOS expression accounts for the hypotensive effect of ethanol in female rats. J Pharmacol Exp Ther 324, 368-375.
El-Mas MM, Abdel-Rahman AA (2007). Role of myocardial contractility and autonomic control in the hypotensive response to a limited access ethanol paradigm in SHRs. Alcohol Clin Exp Res 31, 1071-1079.
El-Mas MM, Abdel-Rahman AA (2007). Intermittent clonidine regimen abolishes tolerance to its antihypertensive effect: a spectral study. J Cardiovasc Pharmacol 49, 174-181.
El-Mas MM, Sharabi FM, El-gowilly SM, Mohy El-Din MM (2007). Inhibition of nitric oxide-guanylate cyclase-dependent and -independent signaling contributes to impairment of β-adrenergic vasorelaxations by cyclosporine. Biochem Pharmacol 73, 359-367.
El-Mas MM, Zhang J, Abdel-Rahman AA (2006). Upregulation of vascular inducible nitric oxide synthase mediates the hypotensive effect of ethanol in conscious female rats. J Appl Physiol 100, 1011-1018.
El-Mas MM, Mohy El-Din MM, El-gowilly SM, Sharabi FM (2005). The α1-adrenergic receptor not DA1-dopaminergic receptor mediates cyclosporine-SKF38393 renovascular interaction. Can J Physiol Pharmacol 83, 1129-1136.
El-Mas MM, Abdel-Rahman AA (2005). Autonomic modulation of altered diurnal hemodynamic profiles in ethanol-fed hypertensive rats. Alcohol Clin Exp Res 29, 499-508.
El-Mas MM, Abdel-Rahman AA (2005). Longitudinal studies on the effect of hypertension on circadian hemodynamic and autonomic rhythms in telemetered rats. Life Sci 76, 901–915.
Omar AG and El-Mas MM (2004). Time-domain evaluation of cyclosporine interaction with hemodynamic variability. Cardiovasc Drugs Therapy, 18, 461-468.
El-Mas MM and Abdel-Rahman AA (2004). Chronic ethanol-clonidine hemodynamic interaction in telemetered spontaneously hypertensive rats. Vascul Pharmacol 41, 107-113.
El-Mas MM, Abdel-Rahman AA (2004). Differential modulation by estrogen of α2-adrenergic and I1-imidazoline receptor-mediated hypotension in female rats. J Appl Physiol 97, 1237-1244.
El-Mas MM, Abdel-Rahman AA (2004). Contrasting effects of chronic ethanol feeding on centrally- and peripherally-evoked hypotension in telemetered female rats. Vascul Pharmacol 41, 59-66.
El-Mas MM, Abdel-Rahman AA (2004). Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability. J Cardiovasc Pharmacol 43, 607-615.
El-Mas MM, Mohy El-Din MM, El-gowilly SM, Sharabi FM (2004). Regional and endothelial differences in the cyclosporine attenuation of adenosine receptor-mediated vasorelaxations. J Cardiovasc Pharmacol 43, 562-573.
El-Mas MM, Mohy El-Din MM, El-gowilly SM, Sharabi FM (2004). Relative roles of endothelial relaxing factors in cyclosporine-induced impairment of cholinergic and β-adrenergic renal vasodilations. Eur J Pharmacol 487, 149-158.
El-Mas MM, Abdel-Rahman AA (2004). Chronic ethanol administration attenuates imidazoline I1 or α2-adrenoceptor-mediated reductions in blood pressure and hemodynamic variability in hypertensive rats. Eur J Pharmacol 485, 251-262.
El-Mas MM, Rekik M, Abdel-Rahman AA, Mustafa JS (2003). Chronic ethanol feeding potentiates α1-adrenoceptor responsiveness in SHR aortas. Clin Exp Hypertens 25, 381-393.
El-Mas MM, Abdel-Rahman AA (2003). Effects of chronic ethanol feeding on clonidine-evoked reductions in blood pressure, heart rate, and their variability: Time-domain analyses. J Pharmacol Exp Ther 306, 271-278.
El-Mas MM, Afify EA, Omar AG, Mohy El-Din MM, Sharabi FM (2003). Testosterone depletion contributes to cyclosporine-induced chronic impairment of acetylcholine renovascular relaxations. Eur J Pharmacol 468, 217-224.
Rekik M, El-Mas MM, Mustafa SJ, Abdel-Rahman AA (2002). Role of endothelial adenosine receptor-mediated vasorelaxation in ethanol-induced hypotension in hypertensive rats. Eur J Pharmacol 452, 205-214.
El-Mas MM, Afify EA, Omar AG, Sharabi FM (2002). Cyclosporine attenuates the autonomic modulation of reflex chronotropic responses in conscious rats. Can J Physiol Pharmacol 80, 766-776.
El-Mas MM, Afify EA, Omar AG, Sharabi FM (2002). Cyclosporine adversely affects baroreflexes via inhibition of testosterone modulation of cardiac vagal control. J Pharmacol Exp Ther 301, 346-354.
El-Mas MM, Afify EA, Mohy El-Din MM, Omar AG, Sharabi FM (2001). Testosterone facilitates the baroreceptor control of reflex bradycardia: role of cardiac sympathetic and parasympathetic components. J Cardiovasc Pharmacol 38, 754-763.
- El-Mas MM, Abdel-Rahman AA (2001). An association between the estrogen-dependent hypotensive effect of ethanol and an elevated brainstem c-jun mRNA in female rats. Brain Res 912, 79-88.
- El-Mas MM, Abdel-Rahman AA (2001). Effect of long-term ethanol feeding on brainstem a2-receptor binding in Wistar-Kyoto and spontaneously hypertensive rats. Brain Res 900, 324-328.
El-Mas MM, Abdel-Rahman AA (2001). Evidence for the involvement of central I1-imidazoline receptor in ethanol counteraction of clonidine hypotension in spontaneously hypertensive rats. J Cardiovasc Pharmacol 38, 417-426.
Zhang J, El-Mas MM, Abdel-Rahman AA (2001). Imidazoline I1 receptor-induced activation of phosphatidylcholine‑specific phospholipase C elicits mitogen‑activated protein kinase phosphorylation in PC12 cells . Eur J Pharmacol 415, 117-125.
El-Mas MM, Abdel-Rahman AA (2000). Clonidine diminishes c-jun gene expression in the cardiovascular sensitive areas of the rat brainstem. Brain Res 856, 245-249.
El-Mas MM, Abdel-Rahman AA (2000). Radiotelemetric evaluation of the hemodynamic effects of long-term ethanol in spontaneously hypertensive and Wistar-Kyoto rats. J Pharmacol Exp Ther 292, 944-951.
El-Mas MM, Abdel-Rahman AA (2000). Ovariectomy alters the chronic hemodynamic and sympathetic effects of ethanol in radiotelemetered female rats. Clin Exp Hypertens 22, 109-126.
El-Mas MM, Abdel-Rahman AA (1999). Role of the sympathetic control of vascular resistance in ethanol-clonidine hemodynamic interaction in SHRs. J Cardiovasc Pharmacol 34, 589-596.
El-Mas MM, Abdel-Rahman AA (1999). Sexually dimorphic hemodynamic effects of intragastric ethanol in conscious rats. Clin Exp Hypertens 21, 1429-1445.
Abdel-Kreem MFM, El-Mas MM (1999). Benzene-1,4-bis [1-(substituted phenethylamino)-cyclohexanes]: potential a2-adrenoceptor probes. Alex J Pharm Sci 13, 47-52.
El-Mas MM, Abdel-Rahman AA (1999). Estrogen-dependent hypotensive effects of ethanol in conscious female rats. Alcohol Clin Exp Res 23, 624-632.
Mohamed MK, El-Mas MM, Abdel-Rahman AA (1999). Estrogen enhancement of baroreflex sensitivity is centrally mediated. Am J Physiol 276, 45, R1030-R1037.
El-Mas MM (1999). Ethanol abolishes clonidine-induced impairment of baroreflex control of heart rate in conscious rats. Gen Pharmacol 32, 207-214.
El-Mas MM, Elmallah AI, Omar AG, Sharabi F (1999). Dopamine modulates peripheral purinergic neurotransmission through multiple presynaptic receptors: tissue-dependent effects. Pharmacol Res 39, 11-19.
El-Mas MM, Abdel-Rahman AA (1999). Acute hemodynamic effects of ethanol in conscious spontaneously hypertensive and normotensive rats. Alcohol Clin Exp Res 23, 285-292.
El-Mas MM, Abdel-Rahman AA (1999). Ethanol counteraction of I1-imidazoline but not alpha-2 adrenergic receptor-mediated reduction in vascular resistance in conscious spontaneously hypertensive rats. J Pharmacol Exp Ther 288, 455-462.
El-Mas MM, Abdel-Rahman AA (1998). Estrogen enhances baroreflex control of heart rate in conscious ovariectomized rats. Can J Physiol Pharmacol 76, 381-386.
El-Mas MM, Abdel-Rahman AA (1998). Ethanol selectively counteracts hypotension evoked via central I1-imidazoline but not a2-adrenergic receptor activation in spontaneously hypertensive rats. J Cardiovasc Pharmacol 32, 382-389.
El-Mas MM, Abdel-Rahman AA (1998). Ovariectomy abolishes ethanol-induced impairment of baroreflex control of heart rate in conscious rats. Eur J Pharmacol 349, 253-261.
El-Mas MM (1998). Facilitation of reflex bradycardia does not contribute to the enhanced hypotensive effect of clonidine in aortic barodenervated rats. J Cardiovasc Pharmacol 31, 869-875.
El-Mas MM, Daabees TT, El-Gowelli HM, Abdel-Galil AA (1997). Enhanced endothelial nitric oxide activity contributes to the reduced responsiveness of vascular a1-adrenoceptors following aortic barodenervation. Eur J Pharmacol 337, 235-243.
El-Mas MM, Abdel-Rahman AA (1997). Role of cardiac output in ethanol-evoked attenuaion of centrally-mediated hypotension in conscious rats. Hypertension 30, 288-294.
El-Mas MM, Abdel-Rahman AA (1997). Aortic barodenervation upregulates a2-adrenoceptors in the nucleus tractus solitarius and rostral ventrolateral medulla: an autoradiographic study. Neuroscience 79, 581-590.
El-Mas MM, Abdel-Galil AA, El-Gowelli HM, Daabees TT (1997). Short-term aortic barodenervation diminishes a1-adrenoceptor reactivity in rat aortic smooth muscle. Eur J Pharmacol 322, 201-210.
El-Mas MM, Abdel-Rahman AA (1997). Contrasting effects of urethane, ketamine and thiopental anesthesia on ethanol-clonidine hemodynamic interaction. Alcohol Clin Exp Res 21, 19-27.
Elmallah AI, Sharabi F, Omar AG, El-Mas MM (1995). Prazosin-induced blockade of extraneuronal uptake facilitates dopaminergic modulation of muscle twitches in rat vas deferns. J Pharm Pharmacol 47, 932-936.
El-Mas MM, Abdel-Rahman AA (1995). Upregulation of imidazoline receptors in the medulla oblongata accounts for the enhanced hypotensive effect of clonidine in aortic baroenervated rats. Brain Res 691, 195-204.
El-Mas MM (1995). Oral and injectable hormonal contraceptives in association with breast cancer. Alex J Pharm Sci 9, 75-78.
El-Mas MM, Carroll RG, Abdel-Rahman AA (1994). Centrally-mediated reduction in cariac output elicits the enhanced hypotensive effect of clonidine in conscious aortic barodenervated rats. J Cardiovasc Pharmacol 24, 184-193.
El-Mas MM (1994). Influence of anesthesia on baroreflex-mediated control of heart rate. Alex J Pharm Sci 8, 99-104.
Fahim M, El-Mas MM, Abdel-Rahman AA, Mustafa SJ (1994). Influence of aortic baroreceptor denervation on adenosine receptor-mediated relaxation of isolated rat aorta. Eur J Pharmacol 254, 183-191.
El-Mas MM, Tao S, Carroll RG, Abdel-Rahman AA (1994). Ethanol-clonidine hemodyamic interaction in normotensive rats is modified by anesthesia. Alcohol 11, 307-314.
El-Mas MM, Carroll RG, Abdel-Rahman AA (1993). Blood pressure normalization in carotid barodenervated rats: role of cardiac output. Can J Physiol Pharmacol 71, 783-790.
El-Mas MM, Abdel-Rahman AA (1993). Role of NMDA and non-NMDA receptors in the nucleus tractus solitarius in the depressant effect of ethanol on baroreflexes. J Pharmacol Exp Ther 266, 602-610.
El-Mas MM, Abdel-Rahman AA (1993). Direct evidence for selective involvement of aortic baroreceptors in ethanol-induced impairment of baroreflex control of heart rate. J Pharmacol Exp Ther 264, 1198-1205.
Abdel-Rahman AA, Carroll RG, El-Mas MM (1992). Role of the sympathetic nervous system in alcohol-guanabenz hemodynamic interaction. Can J Physiol Pharmacol 70, 1217-1224.
El-Mas MM, Abdel-Rahman AA (1992). Role of aortic baroreceptors in ethanol-induced impairment of baroreflex control of heart rate in conscious rats. J Pharmacol Exp Ther 262, 157-165.
Bedwell AM, El-Mas M, Hughes IE (1992). Effect of cocaine on tritium overflow evoked from vasa deferentia previously loaded with [3H]noradrenaline by stimulation using different types of electrodes. J Pharm Pharmacol 44, 235-238.
El-Mas M, Hughes IE (1990): Effect of blockade of noradrenaline re-uptake on evoked tritium overflow from mouse vasa deferentia and rat cortex slices. Br J Pharmacol 101, 762-768.
El-Mas M, Goodall J, Hughes IE (1989). On the mechanism involved in the ability of meptazinol to potentiate the effects of sympathetic nerve stimulation. J Pharm Pharmacol 41, 242-246.
Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A, Zeitoun R (1987). Effects of andursil, ranitidine and prostaglandin E2 on indomethacin induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 69-78.
Rashida Z, Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A (1987). Synergistic effect of combined antacid and ranitidine treatment on restraint induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 79-91.
Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A, Zeitoun R (1987). Protective effect of hyoscine against stress and indomethacin induced gastric ulcers in the rat. Bull Alex Fac Med, XXIII 1, 93-101.
(C) Published Abstracts (148)
El-Mas M, El-Naggar AE, Helmy MM, El-Gowilly SM. Central PI3K/MAPKs Pathway Provokes the Adenosine A3 Receptor Counteraction of Cholinergic Defenses Against Cardiovascular Aberrations in Septic Rats. J Pharmacol Exp Ther June 2024, 389 (S3) 470; DOI: https://doi.org/10.1124/jpet.470.876150.
El-Mas M, Morgaan HA, Sallam MY, El-Gowelli HM, El-Gowelly SM. Pharmacologic and Endotoxic Reprogramming of Renal Vasodilatory, Inflammatory, and Apoptotic Blemishes in Weaning Preeclamptic Dams. J Pharmacol Exp Ther June 2024, 389 (S3) 471; DOI: https://doi.org/10.1124/jpet.471.876580.
El-Mas M, El-Naggar AE, Helmy MM, El-Gowilly SM. Adenosine A3 Receptors Offset the Nicotine Amelioration of Sepsis-Induced Brainstem Inflammation and Depressed Reflex Bradycardia. J Pharmacol Exp Ther June 2024, 389 (S3) 074; DOI: https://doi.org/10.1124/jpet.074.876400.
El-Mas M, Abdelnaby M, Sallam MY, Helmy MM, El-Gowelli HM. Central Inflammatory and Oxidative Signals Contribute to the Morphine Exacerbation of Cardiovascular Hallmarks of Sepsis in Rats. J Pharmacol Exp Ther June 2024, 389 (S3) 073; DOI: https://doi.org/10.1124/jpet.073.954810.
El-Mas M, Khalifa AA, Elblehi SS, Elsokkary NH, Ali MA. Combined Remote Ischemic Preconditioning and Erythropoietin Better Protect Against Lung Injury Induced by Skeletal Ischemia Reperfusion: Role of NLRP3 Inflammasome. J Pharmacol Exp Ther June 2024, 213; DOI: https://doi.org/10.1124/jpet.213.992820.
El-Mas M, Abuiessa SA, Elhamammy RH, El-Deeb NM, Abdelhady SA. The HMGB1/MAPKs/Nrf2 signaling arbitrates hepatoprotection conferred by celecoxib in preeclamptic weaning rats. J Pharmacol Exp Ther June 2023, 385 (S3) 21; DOI: https://doi.org/10.1124/jpet.122.144680.
El-Mas M, Kassem AB, El-Bassiouny NA, Helmy MW, El-Kerm Y, Serageldin MA. Metformin alleviates chemotherapy-induced toxicities in non-diabetic breast cancer patients: a randomized controlled study. J Pharmacol Exp Ther June 2023, 385 (S3) 247; DOI: https://doi.org/10.1124/jpet.122.159900.
El-Mas M, Ali MA, El-Sokkary NH, Elblehi SS, Khalifa AA. Mitochondrial modulation of amplified preconditioning influences of remote ischemia plus erythropoietin against skeletal ischemia/reperfusion injury in rats. J Pharmacol Exp Ther June 2023, 385 (S3) 421; DOI: https://doi.org/10.1124/jpet.122.189290.
Wedn AM, El-Gowilly SM, El-Mas MM. Fetomaternal Cardiovascular and Renal Adverse Outcomes of Recurrent Preeclampsia in Rats. FASEB J, 13 May 2022, 36, Issue S1 (Experimental Biology 2022 Meeting Abstracts).
El-Naggar AE, Helmy MM, El-Gowilly SM, El-Mas MM. Central Adenosine A1 Receptors Arbitrate the Nicotine Counteraction of Cardiovascular and Autonomic Dysfunctions in Septic Rats. FASEB J, 13 May 2022, 36, Issue S1(Experimental Biology 2022 Meeting Abstracts).
Abuiessa SA, Helmy MM, El-Gowelli HM, El-Gowilly SM, El-Mas MM. RAS Imbalances Account for Baroreflex Dysfunction and Neuroinflammation Induced by Postpartum Endotoxemia in Weaning Preeclamptic Rats. FASEB J, 13 May 2022, 36, Issue S1(Experimental Biology 2022 Meeting Abstracts).
Morgaan HA, Sallam MY, El-Gowelli HM, El-Gowilly SM, El-Mas MM. Consequent Endotoxemia Relieves Abnormalities in Renal Vasoconstriction and AT1/ACE/ACE2 Signaling in Preeclamptic Offspring: Roles of Sex and Antenatal Ang 1-7 Therapy. FASEB J, 13 May 2022, 36, Issue S1(Experimental Biology 2022 Meeting Abstracts).
Abuiessa SA, Ayieng’a EO, Elblehi SS, El-Gowilly SM, Afify EA, El-Mas MM. Morphine Aggravates Inflammatory, Behavioral, and Hippocampal Structural Deficits in Septic Rats. FASEB J, 13 May 2022, 36, Issue S1(Experimental Biology 2022 Meeting Abstracts).
Abuiessa SA, Ayieng’a EO, Elblehi SS, El-Gowilly SM, Afify EA, El-Mas MM. Upregulation of Hippocampal MAPKERK/NFκB Signaling Accounts for the Opioid Receptor-dependent Incitement of Cognitive Impairment in Septic Rats. FASEB J, 13 May 2022, 36, Issue S1(Experimental Biology 2022 Meeting Abstracts).
Morgaan HA, El-Gowilly SM, El-Mas MM. Preeclamptic programming unevenly modifies hemodynamic and renovascular outcomes of endotoxemia in rat offspring: modulation by sex and antenatal therapies. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Wedn AM, Abuiessa SA, Helmy MM, El-Gowilly SM, El-Mas MM. Maternal and fetal defects of gestational angiotensin 1‐7 receptor antagonism: a possible preclinical model of preeclampsia. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Abuiessa SA, Helmy MM, El-Gowilly SM, El-Mas MM. Dysregulated ACE/Ang II And ACE2/Ang 1‐7 signalling provokes cardiovascular and neuroinflammatory outcomes of endotoxemia in weaning preeclamptic rats. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Abuiessa SA, Helmy MM, El-Gowilly SM, El-Mas MM. Gestationally administered RAS modulators reprogram endotoxic cardiovascular and inflammatory profiles in adult offspring of preeclamptic rats. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Habib YH, Abdelhady SA, Gowayed MA, El-Deeb NM, Darwish IE, El-Mas MM. Prenatal endothelin or thromboxane receptor antagonism surpasses sympathoinhibition in managing cardiovascular and renal malfunctions in preeclamptic rats. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Habib YH, Gowayed MA, Abdelhady SA, El-Deeb NM, Darwish IE, El-Mas MM. Modulation by antenatal therapies of cardiovascular and renal programming in male and female offspring of preeclamptic rats. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Abdelhady SA, Ali MA, Yacout DM, Kandil LS, Elblehi SS, El-Mas MM. Antenatally administered NSAIDs improve renal cyclooxygenase and antiangiogenic profiles in rats with preeclampsia. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Abdelhady SA, Ali MA, Yacout DM, Kandil LS, Elblehi SS, El-Mas MM. Reprogramming by gestational NSAIDs of cardiovascular defects in preeclamptic rats: roles of cyclooxygenase and antiangiogenic trails. FASEB J 2021, 35, Issue S1 (Experimental Biology 2021 Meeting Abstracts).
Elzokm SS, Fouda MA, Abdel Moneim RA, El-Mas MM. Directionally Opposite Effects Of Cyclosporine And Sirolimus On Endotoxic Nephrotoxicity In Rats. The FASEB J 2020, 34, Issue S1.
Elzokm SS, Fouda MA, Abdel Moneim RA, El-Mas MM. Androgen‐Dependent Provocation by Tacrolimus of Nephrotoxic and Inflammatory Consequences of Endotoxemia in Rats. FASEB J 2020, 34, Issue S1.
Elzokm SS, El-Deeb NM, Abdel Moneim RA, Fouda MA, El-Mas MM. Endotoxic hepatotoxicity in rats is exacerbated by tacrolimus and diminished by cyclosporine or sirolimus: modulation by androgenic hormones. FASEB J 2020, 34, Issue S1.
Abuiessa SA, El-Gowilly SM, Helmy MM, El-Mas MM. Cardiovascular Programming by Preeclampsia Sensitizes Mother Rats to Hemodynamic and Cardiac Autonomic Depressant Effects of Postpartum Endotoxemia. FASEB J 2020, 34, Issue S1.
Abuiessa SA, Wedn AM, El-Gowilly SM, Helmy MM, El-Mas MM. Preeclamptic Fetal Programming Alters Neuroinflammatory and Cardiovascular Consequences of Endotoxemia in Sex Specific Manners. FASEB J 2020, 34, Issue S1.
Sallam MY, El-Gowilly SM, El-Mas MM. Cardiac and Medullary Neuroinflammatory Pathways Trigger Androgenic Incitement of Cardiovascular Sequels of Endotoxemia in Rats. FASEB J 2020, 34, Issue S1.
Sallam MY, El-Gowilly SM, El-Mas MM. Inconsistent effects of surgical and chemical castration on arterial baroreceptor dysfunction and cardiac and brainstem inflammation in endotoxic rats. FASEB J 2020, 34, Issue S1.
Abdelhady SA, Ali MA, Al-Shafie TA, Abdelmawgoud EM, Yacout DM, El-Mas MM. Montelukast Potentiates the Antiinflammatory Effect of NSAIDs in the Rat Paw Formalin Model and Simultaneously Minimizes the Risk of Gastric Damage. FASEB J 2020, 34, Issue S1.
Wedn AM, El-Gowilly SM, El-Mas MM. The alpha7-nAChRs and Heme Oxygenase-1 Pathway Are Key Mediators of Nicotine Protective Actions During Endotoxemia. Int J Toxicol 2020, 39 (1), 45.
Youssef ME, El-Mas MM, Abdelrazek HM, El-Azab MF. α7-nAChR-Mediated Therapeutic Angiogenesis Accounts for the Advantageous Effect of Low Nicotine Doses Against Myocardial Infarction in Rats. FASEB J April 2019, 33, Issue 1, suppl 01: 679.1
Sallam MY, El-Mas MM, El-Gowilly SM. Nicotinic Acetylcholine Receptors of α7 and α4β2 Types Mediate the Nicotine Counteraction of Impaired Baroreceptor Function in Endotoxic Rats. FASEB J April 2019, 33, Issue 1, suppl 01: 511.2
Wedn AM, El-Gowilly SM, El-Mas MM. The Compromised Renal Vasodilations of Adenosinergic Origin in Endotoxic Rats is Reversed by Nicotine: Role of the nAChRs/Heme Oxygenase-1 Pathway. FASEB J April 2019, 33, Issue 1, suppl 01: 513.11
El-Lakany MA, Fouda MA, El-Gowelli HM, El-Mas MM. Nicotine Dose-Dependently Uncovers Endotoxic Cardiovascular Manifestations of Hypotension and Autonomic Dysfunction in Female Rats. FASEB J April 2019, 33, Issue 1, suppl 01: 513.12
El-Lakany MA, Fouda MA, El-Gowelli HM, El-Mas MM. Estrogen Receptor-α Counterbalances the Endotoxic Inflammatory Response and Associated Arterial Baroreflex Dysfunction in Ovariectomized Rats. FASEB J April 2019, 33, Issue 1, suppl 01: 513.5 (oral presentation)
Wedn AM, El-Gowilly SM, El-Mas MM. El-Mas. Prolonged Exposure of Rats to Bacterial Lipopolysaccharide Accelerates Mortality and blunts Hemodynamic and Renal Effects of Endotoxemia in Sex-Specific Fashions. FASEB J April 2019, 33, Issue 1, suppl 01: 513.4
El-Yazbi AF2, Fouda MA, Mroueh Ali, El-Mas MM. Differential Modulation by Adenosine A1 and A3 Receptors of Acute Endotoxemia-Induced Hemodynamics, Cardiac Autonomic Impairment, and oxidative damage. FASEB J April 2019, 33, Issue 1, suppl 01: 513.2
Wedn AM, El-Gowilly SM, El-Mas MM. Activation of α7-nAChRs counteracts the inflammatory and renal vasoconstrictor hyporeactivity in endotoxic rats via heme oxygenase/carbon monoxide upregulation. Asian Conference on Science, Technology & Medicine (ACSTM), Dubai, UAE, February 12-14, 2019 (oral presentation).
Sallam MY, El-Gowilly SM, Fouda MA, Abd-Alhaseeb MM, El-Mas MM. Central α7/α4β2 AChR signaling ameliorates the inflammatory, hypotensive and cardiovascular manifestations of endotoxemia in conscious male rats. 5th Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt, January 28-30, 2019, PP. 123 (https://www.fue.edu.eg/5thfue-icps2019/).
El-Lakany MA, Fouda MA, El-Gowelli HM, El-Mas MM. Female gonadal hormones diversely modulate hemodynamics, cardiac inflammation and impaired autonomic control in endotoxic rats with surgical menopause. 5th Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt, January 28-30, 2019, PP. 124 (https://www.fue.edu.eg/5thfue-icps2019/).
Wedn AM, El-Gowilly SM, El-Mas MM. Heme byproducts distinctly contribute to the α7-nAChR-dependent counteraction of inflammatory and renal vasoconstrictor hyporeactivity in endotoxic rats. 5th Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt, January 28-30, 2019, PP. 56 (https://www.fue.edu.eg/5thfue-icps2019/).
Sallam MY, El-Gowilly SM, Fouda MA, Abd-Alhaseeb MA, El-Mas MM. Central Cholinergic Pathways Diminish the Hypotensive and Cardiac Autonomic Depressant Effects of Endotoxemia in Male Rats: Role of Medullary NFκB/α7/α4β2 AChR Signaling. FASEB J April 2018 32:697.2
Wedn AM, El-Gowilly SM, El-Mas MM. Sex-unrelated counteraction by nicotine of the endotoxemia-evoked facilitation of renal vasodilator capacity in rats: roles of α7/α4β2 nAChRs and HSP70. FASEB J April 2018 32:562.8
Wedn AM, El-Gowilly SM, El-Mas MM. The α7-nAChRs/heme oxygenase/carbon monoxide pathway arbitrates nicotine counteraction of the inflammatory and renal vasoconstrictor hyporeactivity in endotoxic rats. FASEB J April 2018 32:568.9
El-Mas MM, El-Lakany MA, Fouda MA, El-Gowelli HM. The Provoked Cardiovascular and Autonomic Effects of Endotoxemia in Ovariectomized Rats Are Distinctly Affected by Estrogen and Progesterone Supplementation. FASEB J April 2018 32:697.1
Helmy MM, Helmy MW, El-Mas MM. Upregulation of cystathionine-γ-lyase/hydrogen sulfide pathway underlies the celecoxib counteraction of cyclosporine-induced hypertension and renal insult in rats. FASEB J April 2018 32:562.9
El-Mas MM, El-Bassossy H, Awan Z. Prenatal exposure to cyclosporine impair cardiac function in neonates FASEB J April 2017 31:997.1
Sallam MY, El-Gowilly SM, Abdel-Galil AA, El-Mas MM. Amelioration by GABAB receptors of the cyclosporine-evoked counteraction of endotoxic cardiovascular manifestations in conscious rats. FASEB J April 2017 31:827.4
Helmy MW, Helmy MM, El-Mas MM. Enhanced Lipoxygenase/LTD4 Activity Accounts For The Exaggerated Hypertensive And Nephrotoxic Effects Of Cyclosporine Plus Indomethacin In Rats FASEB J April 2017 31:lb54
Ibrahim KS, El-Yazbi AF, El-Gowelli HM, El-Mas MM. Heme oxygenase byproducts variably influences myocardial and autonomic dysfunctions induced by the cyclosporine/diclofenac regimen in female rats FASEB J April 2017 31:1070.13
Hammoud SH, Omar AG, Eid AA, El-Mas MM. CYP4A/CYP2C Modulation of the Interaction of Calcium Channel Blockers with Cyclosporine on EDHF-Mediated Renal Vasodilations in Rats FASEB J April 2017 31:998.6
Hammoud SH, Eid AA, Omar AG, El-Mas MM. Molecular Mechanisms of the Protective Effects of Calcium Channel Blockers against Cyclosporine Nephrotoxicity in Rats FASEB J April 2017 31:998.7
Sallam MW, El-Gowilly SM, El-Gowelli HM, El-Mas MM. The α7/α4β2 nAChRs Alleviate The Hypotension And Altered Cardiac Sympathovagal Balance Evoked By Endotoxemia In Male Rats FASEB J April 2017 31:848.3
El-Lakany MA, El-Gowelli HM, Fouda MA, El-Gowilly SM, El-Mas MM. Gonadal Hormone Receptors Underlie The Resistance Of Female Rats To Cardiovascular Complications Of Endotoxemia FASEB J April 2017 31:848.4
El-Mas MM, Ibrahim KS, El-Yazbi AF, El-Gowelli HM. Modulation by NADPH-ox/Rho-kinase signaling of the cyclosporine-NSAIDs interactions on blood pressure and baroreflexes in female rats FASEB J April 2017 31:848.1
El-Mas MM. Endothelin modulation of the cyclosporine/NSAIDs cardiovascular and renal interactions. J Clin Toxicol 2016, 6:6(suppl), page 54.
El-Mas MM, Ibrahim KS, El-Yazbi AF, El-Deeb NM, El-Gowelli HM. Modulation by NADPH Oxidase/Rho-Kinase Oxidative Pathway of Chronic Cyclosporine- Diclofenac Hemodynamic Interaction in Female Rats FASEB J April 2016 30:716.8
El-Mas MM, Sallam MY, Abdel-Galil AA, El-Gowilly SM (2016). Central GABAA Receptors Provoke Inflammatory and Cardiovascular Consequences of Endotoxemia in Conscious Rats. FASEB J April 2016 30:1200.4
El-Mas MM, Sallam MY, Abdel-Galil AA, El-Gowilly SM (2016). Cyclosporine Ameliorates Reductions in Blood Pressure and Heart Rate Variability Caused by Endotoxemia in Rats: Modulation by Central PI3K/sGC/MAPKs Signaling FASEB J April 2016 30:1200.3
El-Mas MM, El-Bassossy HM, Banjar ZM. Sexual dimorphism in left ventricular and electrocardiographic effects of chronic cyclosporine in rats FASEB J April 2016 30:716.7
Fouda MA, El-Gowelli El-Gowelli HM, El-Gowilly SM, El-Mas MM. Hemin blunts the depressant effect of chronic nicotine on reflex tachycardia in female rats via activation of central NOS/PI3K pathway. British Pharmacological Society Meeting, London, U.K., Dec 2015 (Proceedings of the British Pharmacological Society at http://www.pA2online.org/abstracts/Vol13Issue3abst014P.pdf).
El-Mas MM, Helmy MW, Helmy MM. Additive Renoprotective Effects Of Pioglitazone And Fenofibrate Against Cisplatin-Induced Renal Failure: PPARs/TNF-α Modulation. FASEB J April 2015 29:938.5
Sallam MW, El-Gowilly SM, Abdel-Galil AA, El-Mas MM. Central Pathways of MAPKp38 and MAPKJNK Mediate TNFα/iNOS-Dependent Endotoxic Manifestations of Hypotension and Compromised Heart Rate Variability in Rats. FASEB J April 2015 29:624.4
Ibrahim KS, El-Yazbi AF, El-Gowelli HM, El-Mas MM. Divergent Effects for Celecoxib and Diclofenac on Hemodynamic and Left Ventricular Actions of Cyclosporine in Female Rats. FASEB J April 2015 29:1025.11
El-Mas MM, Abdel-Rahman AA. Ethanol Discontinuation Does Not Fully Reverse Its Chronic Effects on Blood Pressure, Heart Rate, and Their Variability in SHRs: Diurnally-Unrelated Effects. FASEB J April 2015 29:623.11
El-Mas MM, Abdel-Rahman AA. Estrogen-Dependent Upregulation of the Renin Angiotensin System and Constitutive NOS Accounts for Ethanol Enhancement of Enalapril-Evoked Hypotension in Telemetered Female Rats. FASEB J April 2015 29:624.1
Fouda MA, El-Gowelli El-Gowelli HM, El-Gowilly SM, El-Mas MM. Peripheral and central mechanisms of cyclosporine-induced hypertension, 3rd Future University International Conference of Pharmaceutical Sciences, Cairo, Egypt 2015, Feb 9-11.
El-Mas MM. Divergent estrogenic modulation of the nicotine-baroreflex interaction, the 6th International Conference on Natural Toxins, Suez Canal University, Ismailia, Egypt 2014, Dec 15-16.
El-Mas MM, El-Gowelli HM, Elsalakawy LK, El-gowilly SM. Estrogen compromises the facilitatory effect of chronic nicotine on adenosine A2B receptor/K+ channel-mediated renal vasodilations. FASEB J April 2014 28: 837.3
El-Mas MM, Abdel-Rahman AA. Nongenomic effects of estrogen mediate the dose-related myocardial oxidative stress and dysfunction caused by acute ethanol in female rats. FASEB J April 2014 28:652.19
El-Mas MM, Abdel-Rahman AA. Enhanced oxidative stress/DAPK3/Akt/ERK signaling accounts for estrogen exacerbation of cardiac dysfunction caused by ethanol in male rats. FASEB J April 2014 28:652.20
El-Mas MM, El-Gowelli HM, Fouda M, El-gowilly SM.The interplay between heme oxygenase and nitric oxide synthase and downstream PI3K/sGC/ERK signaling ameliorates the estrogen-dependent depressant effect of chronic nicotine on reflex bradycardia. FASEB J April 2014 28:837.2
Nasser S, Elmallah A, Mohy El-Din M, Khedr M, El-Mas MM. Functional angiotensin and endothelin, but not thromboxane, pathways are necessary for the hypertension and baroreflex dysfunction caused by cyclosporine in rats. FASEB J April 2014 28:LB565
Helmy MW, El-Gowelli HM, Abdel-Halim RM, El-Mas MM. Aggravated Nephrotoxicity Evoked By Concurrent Exposure To Cyclosporine And Indomethacin In Rats: Role Of The Endothelin ETA Receptor/TGF-beta/COX-2 Pathway FASEB J April 9, 2013 27:654.10
El-Gowelli HM, Helmy MW, Abdel-Halim RM, El-Mas MM. Celecoxib Offsets The Negative Renal Influences of Cyclosporine Via COX-2/Endothelin ETB Receptor crosstalk FASEB J April 9, 2013 27:654.9
El-Mas MM, Abdel-Halim RM, Helmy MW, El-Gowelli HM. Endothelin ETA/ETB receptors modulate the hemodynamic interaction of cyclosporine with selective and nonselective nonsteroidal antiinflammatory drugs in rats FASEB J April 9, 2013 27:654.8
El-Mas MM, Abdel-rahman AA. The ERK/MAPK-Dependent Pressor Effect Of Intra-RVLM Ethanol Is Tonically Attenuated By Local Phosphatases In Normotensive Rats FASEB J April 9, 2013 27:654.7
Gohar EY, El-gowilly SM, El-Gowelli HM, El-Mas MM. Nicotine Paradoxically Alters The Facilitatory Action Of Estrogen And Progesterone On Adenosine Receptor-Mediated Renal Vasodilations FASEB J April 9, 2013 27:654.6
El-Mas MM, El-Gowelli HM, Fouda MA, El-Gowilly SM. Modulation Of The Baroreflex Depressant Effect Of Chronic Nicotine In Female Rats By Nitric Oxide Synthase And Heme Oxygenase FASEB J April 9, 2013 27:654.5
Fan M, El-Mas MM, Abdel-rahman AA. Preserved Left Ventricular Performance In Spontaneously Hypertensive Rats Following Preload And Afterload Challenges FASEB J April 9, 2013 27:654.4
El-Mas MM, Abdel-rahman AA. The Estrogen-Mediated Control Of Blood Pressure And Cardiovascular Autonomic Control Are Differentially Modulated By Endothelial And Neuronal Nitric Oxide Synthases FASEB J April 9, 2013 27:654.3
El-Mas MM, Abdel-rahman AA. Cardiovascular Autonomic Activity Modulation By Nitric Oxide Synthases Mediates The Augmented Enalapril-Evoked Hypotension In Ethanol-Fed Female Rats FASEB J April 9, 2013 27:654.2
Nasser SA, Elmallah AI, Sabra R, Khedr MM, Mohy El-Din MM, El-Mas MM. On The Mechanism Of The Cyclosporine-Evoked Facilitation Of The Vasoconstrictor Activity Of Angiotensin II In The Rat Aorta FASEB J April 9, 2013 27:lb593
Nasser SA, Elmallah AI, Sabra R, Khedr MM, Mohy El-Din MM, El-Mas MM. Endothelin ETA Receptor-Mediated Nitric Oxide Synthase Inhibition Underlies Cyclosporine Impairment Of Cholinergic Vasorelaxations In Rats FASEB J April 9, 2013 27:lb597
El-Mas MM. Gender and hormonal specificities of the nicotine interaction with cardiac reflexes. International Conference on Advanced Basic and Applied Sciences, Hurghada, Egypt, Nov 2012, pp. 35-36.
El-Mas MM, El-gowilly SM, Gohar EY, El-Gowelli HM. Influence of chronic nicotine on acetylcholine-evoked renal vasodilations in female rats: dose dependency and ovarian hormonal modulation FASEB J March 29, 2012, 26, 1051.7
El-Mas MM, El-Gowelli HM, Elsalakawy LK, El-gowilly SM. Nitric oxide synthase, but not heme oxygenase, mediates the adenosine a2b receptor-sensitive renal vasodilations in female rats FASEB J March 29, 2012, 26, 1051.6
El-Mas MM, Fan M, Abdel-Rahman AA. Role of rostral ventrolateral medullary erk/jnk/p38 mapk signaling in the pressor effects of ethanol and its oxidative product acetaldehyde in shrs FASEB J March 29, 2012, 26, 1115.14
El-Mas MM, Abdel-Rahman AA. Enhanced catabolism to acetaldehyde in rostral ventrolateral medullary neurons accounts for the pressor effect of ethanol in shrs FASEB J March 29, 2012, 26, 1115.13
El-Mas MM, El-Gowelli HM, Fouda MA, El-gowilly SM. Inhibition of the estrogen-mediated cardiac vagal control accounts for the baroreflex depressant effect of chronic nicotine in female rats FASEB J March 29, 2012, 26, 1124.9
El-Mas MM, El-Gowelli HM, Fouda MA, Helmy MM. Dose Dependency and autonomic modulation of the depressant effect of chronic nicotine on reflex chronotropic responses in female rats. FASEB J 2011, 25, 1084.1
El-Mas MM, Omar AG, Helmy MM, Mohy El-Din MM. Autonomic and redox states modulate the moxonidine-cyclosporine hemodynamic and baroreflex interactions. FASEB J 2011, 25, 1084.2
El-Mas MM, El-gowilly SM, Fouda MA, Saad EI. Central adenosine receptors differentially contribute to the nicotine-induced attenuation of reflex tachycardic responses to baroreceptor unloading. FASEB J 2011, 25, 1084.3
El-Mas MM, Fan M, Abdel-Rahman AA. Modulatory roles of constitutive and inducible NOS in the ethanol-evoked hypotension and cardiac autonomic dysfunction in female rats. FASEB J 2011, 25, 1084.4
El-Mas MM, Abdel-Rahman AA. Myocardial contractility and autonomic imbalances contribute to the estrogen-dependent hypotensive effect of chronic ethanol in rats FASEB J 2011, 25, 1084.5
Abd-Elrahman KS, El-Gowelli HM, , Saad EI, Abdel-Galil AA, El-Mas MM. PPARγ dependence of the cyclosporine-isoprenaline renovascular interaction: roles of nitric oxide synthase and heme oxygenase. FASEB J 2011, 25, 1087.8
El-Mas MM, El-gowilly SM, Fouda MA, and Saad EI. Acute nicotine attenuates reflex tachycardia in male rats via inhibition of baroreceptor-mediated cardiac sympathetic control. FASEB J 2010, 24, 961.2
El-Mas MM, El-gowilly SM, Fouda MA, and Saad EI. Estrogen Protects Female Rats Against The Nicotine-Induced Attenuation Of Reflex Tachycardia: Role Of Central Estrogen Receptors. FASEB J 2010, 24, 961.3
El-Mas MM, Omar AG, Helmy MM, and Mohy El-Din MM. Amelioration By Tempol Of The Hypertensive And Baroreflex Depressant Effects Of Cyclosporine In Conscious Rats: Role Of Cardiac Autonomic Control. FASEB J 2010, 24, 961.5.
El-Mas MM, Omar AG, Helmy MM, and Mohy El-Din MM. Modulation Of Cyclosporine-Induced Hypertension By Central Endothelial And Neuronal Nitric Oxide Synthases. FASEB J 2010, 24, 959.10.
El-Mas MM, El-Gowelli HM, Saad EI, Abd-Elrahman KS, and Abdel-Galil AA. Pioglitazone Ameliorates Cyclosporine-Induced Attenuation Of Carbachol Renovascular Vasodilations: Role Of PPAR/Nitric Oxide Synthase Signaling. FASEB J 2010, 24, 959.11.
El-Mas MM, El-Gowelli HM, Harraz OF, Ghazal AM, and Mohy El-Din MM. Adenosinergic Modulation Of The Imidazoline I1-Receptor-Dependent Hypotensive Effect Of Ethanol In Acute Renal Failure. FASEB J 2010, 24, 961.10
El-Mas MM, El-Gowelli HM, Saad EI, Abd-Elrahman KS, and Abdel-Galil AA. Improved Antioxidant And Lipid Profiles Underlie The Protective Effect Of Pioglitazone Against Cyclosporine-Induced Endothelium Dysfunction In Isolated Rat Aortas. FASEB J 2010, 24, 961.13.
El-Mas MM, Abdel-Rahman AA. Longitudinal assessment of the modulatory effect of estrogen on blood pressure and cardiac autonomic activity in female rats. FASEB J 2009, 23, 577.8
El-Mas MM, Fan M, Abdel-Rahman AA. Upregulation of cardiac NOS due to endotoxemia and vagal overactivity contributes to the hypotensive effect of chronic ethanol in female rats. FASEB J 2009, 23, 932.16
Nasr MA, El-gowilly SM, El-Mas MM (2008). A comparative study of the protective effect of simvastatin and moxonidine against renovascular toxicity induced by smoking in rats. FASEB J 22, Abstract # 1129.11
El-gowilly SM, Ghazal AM, Goher EY, and El-Mas MM (2008). Additive impairment of β-adrenoceptor-mediated renal vasodilation by nicotine and cyclosporine. FASEB J 22, Abstract # 1129.10
El-Mas MM, Omar AG, Helmy MM, Mohy El-Din MM (2008). Nitric oxide modulation of central imidazoline I1 receptors accounts for the hypertensive effect of cyclosporine in rats. FASEB J 22, Abstract # 1129.9.
El-Mas MM, El-gowilly SM, Goher EY, Ghazal AM (2008). Gender and estrogen specificity of the renal vasodilatory effect of nicotine in rats. FASEB J 22, Abstract # 1129.8.
El-Mas MM, El-gowilly SM, Goher EY, Ghazal AM (2008). Roles of nitric oxide and K+ channels in the vasodilatory action of nicotine in the rat renal vasculature. FASEB J 22, Abstract # 1129.7.
El-Mas MM and Abdel-Rahman AA (2008). Ethanol feeding enhances the hypotensive action of enalapril in telemetered female rats: Role of bradykinin B2 receptors. FASEB J 22, Abstract # 1129.6.
El-Mas MM, Fan M and Abdel-Rahman AA (2008). Ethanol lowers blood pressure in conscious female rats via enhancing the phosphorylation of myocardial neuronal nitric oxide synthase. FASEB J 22, Abstract # 1129.5.
El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2006). Signaling mechanisms of cyclosporine-induced impairment of β-adrenergic vasorelaxations. BioVision Alexandria, Abstract# 37, pp. 17.
El-Mas MM and Abdel-Rahman AA (2005). Receptor specificity of the negative impact of ethanol on centrally-evoked hypotension in female rats. FASEB J 19 (4), Abstract# 87.7, pp. A102.
El-Mas MM, Zhang J and Abdel-Rahman AA (2005). Upregulation of vascular inducible nitric oxide synthase mediates the hypotensive effect of ethanol in conscious female rats. FASEB J 19 (4), Abstract# 87.6, pp. A101-102.
El-Mas MM and Abdel-Rahman AA (2005). Autonomic modulation of altered diurnal hemodynamic profiles in ethanol-fed hypertensive rats. FASEB J 19 (4), Abstract# 87.5, pp. A101.
El-Mas MM and Abdel-Rahman AA (2005). Intermittent clonidine regimen abolishes tolerance to its antihypertensive effect: a spectral study. FASEB J 19 (4), Abstract# 87.4, pp. A101.
El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2004). Regional and endothelial differences in the cyclosporine attenuation of adenosine receptor-mediated vasorelaxations. FASEB J 18 (5), Abstract#643.7, pp. A982-983.
El-Mas MM and Abdel-Rahman AA (2004). Effects of long-term ovariectomy and estrogen replacement on clonidine-evoked reductions in blood pressure and hemodynamic variability. FASEB J 18 (4), Abstract#404.14, pp. A601-602.
El-Mas MM and Abdel-Rahman AA (2004). Chronic ethanol attenuates I1- or α2-receptor-mediated reductions in blood pressure and hemodynamic variability in hypertensive rats. FASEB J 18 (4), Abstract#404.13, pp. A601.
El-Mas MM and Abdel-Rahman AA (2004). Age-related alterations in circadian hemodynamic rhythms in telemetered wistar-kyoto and spontaneously hypertensive rats. FASEB J 18 (4), Abstract#404.12, pp. A601.
El-Mas MM, Mohy El-Din MM, El-Gowelli S and Sharabi FM (2003). Roles of endothelial relaxing factors in cyclosporine-induced inhibition of cholinergic and β-adrenergic renovascular relaxations. FASEB J 17 (4), Abstract#148.4, pp. A224.
El-Mas MM and Abdel-Rahman AA (2003). Effects of chronic ethanol feeding on clonidine-evoked reductions in blood pressure, heart rate, and their variability: Time-domain analyses. FASEB J 17 (4), Abstract#400.3, pp. A651.
El-Mas MM, Afify EA, Omar AG, Mohy El-Din MM, and Sharabi FM (2003). Testosterone reverses cyclosporine-induced chronic impairment of acetylcholine renovascular relaxations. FASEB J 17 (4), Abstract#386.8, pp. A617.
Abdel-Rahman AA, El-Mas MM (2001). Evidence for the involvement of central I1-imidazoline receptor in ethanol counteraction of clonidine hypotension in SHRs. FASEB J 15 (4), Abstract#202.15, pp. A212.
Rekik M, El-Mas MM, Abdel-Rahman AA, and Mustafa SJ (2000). Long-term ethanol feeding enhances the vasorelaxing effect of adenosine in isolated aorta from spontaneously hypertensive rats. FASEB J 14 (4), Abstract#330-12, pp. A462.
El-Mas MM and Abdel-Rahman AA (1999). Downregulation of a2-adrenoceptors in the nucleus tractus solitarius chronic ethanol feeding contributes to its hemodynamic interaction with a-methyldopa in telemetered spontaneously hypertensive rats. Experimental Biology meeting, Late-Breaking Abstract# 19.
El-Mas MM and Abdel-Rahman AA (1999). Estrogen-dependent hypotensive and sympathoinhibitory effects of ethanol in conscious female rats. FASEB J 13 (5), Abstract#788.7, pp. A1045.
El-Mas MM and Abdel-Rahman AA (1999). Radiotelemetric evaluation of the hemodynamic effects of long-term ethanol feeding in spontaneously hypertensive and wistar kyoto rats. FASEB J 13 (5), Abstract#128.24, pp. A115.
El-Mas MM and Abdel-Rahman AA (1998). Role of the sympathetic control of vascular resistance in the differential effect of ethanol on I1-imidazoline and a2-adrenergic receptor evoked hypotension. Circulation 98 (17), Abstract#2349, pp. I-447.
El-Mas MM and Abdel-Rahman AA (1998). Ovariectomy abolishes ethanol-induced impairment of baroreflex control of heart rate in conscious rats. FASEB J 12 (4), Abstract#2317, pp. A399.
Abdel-Rahman AA, Mohamed MK, and El-Mas MM (1998). Estrogen enhancement of baroreflex sensitivity is centrally mediated. FASEB J 12 (4), Abstract#2316, pp. A398.
Vadlamudi S, Cortright RN, El-Mas MM, Abdel-Rahman AA, and Barakat H (1998). Chronic alcohol feeding differentially alters insulin sensitivity in skeletal muscle and adipocytes in SHRs: Minisymposium. FASEB J 12 (4), Abstract#2058, pp. A354.
El-Mas MM and Abdel-Rahman AA (1997). Contrasting effects of anesthetics on ethanol-clonidine hemodynamic interaction. FASEB J 11 (3), Abstract#2694, pp. A466.
Abdel-Rahman AA and El-Mas MM (1997). Upregulation of brainstem imidazole receptors accounts for the enhanced hypotensive effect of clonidine in aortic denervated rats. Fundam Clin Pharmacol 11 (Suppl 1), 124s-125s.
Sharabi FM, El-Mallah AI, Omar AG and El-Mas MM (1996). Dopamine modulates neurotransmission at periphery through multiple presynaptic receptors: tissue-dependent effects. FASEB J 10 (3), Abstract#2467, pp. A427.
El-Mas MM (1994). Interaction of anesthesia with baroreflex chronotropic responses: sex related effects. Annual Conference of the Egyptian Society of Pharmacology and Experimental Therapeutics, Cairo, Egypt, pp. 8.
Fahim M, El-Mas MM, Abdel-Rahman AA and Moustafa SJ (1993). Diminished arterial smooth muscle response to adenosine analog in aortic baroreceptor denervated rats. XXXII Congress of the International Union of Physiological Sciences, Glasgow, 249.87/P.
El-Mas MM, Carroll RG and Abdel-Rahman AA (1993). Role of cardiac output in blood pressure normalization in carotid barodenervated rats. XXXII Congress of the International Union of Physiological Sciences, Glasgow, 172.14/P.
Abdel-Rahman A-RA, Carroll RG and El-Mas MM (1992). Ethanol reverses clonidine evoked decreases in plasma norepinephrine and arterial pressure in conscious rats. 7th International Catecholamine Symposium, Amsterdam, Abstr. 1.
El-Mas MM and Abdel-Rahman A-RA (1992). Selective involvement of NMDA receptors in ethanol-induced attenuation of baroreflexes. Pharmacologist, 34, 167.
El-Mas M and Hughes IE (1991). Effect of cocaine on 3H-overflow evoked by different types of electrical stimulation of vas deferens loaded with 3H-noradrenaline. Fundam Clin Pharmacol 5: 461.
El-Mas M and Hughes IE (1990). Influence of cocaine on electrically evoked [3H]-NA overflow from noradrenergic nerves: tissue dependent effect. Br J Pharmacol, 99, 178P.
El-Mas M and Hughes IE (1989). Differential effect of cocaine on electrically evoked tritium overflow from mouse vas deferens and rat brain cortical slices. Br J Pharmacol 98, 656P.
Rashida Z, Abou Zeit-Har MS, Bistawroos AE, El-Mas MM and Ghazal A (1985). Synergistic effect of combined antacid and ranitidine treatment on restraint induced gastric ulcers in the rat. Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.
Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A. and Zeitoun R (1985). Protective effect of hyoscine against stress and indomethacin induced gastric ulcers in the rat. Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.
Abou Zeit-Har MS, Bistawroos AE, El-Mas MM, Ghazal A and Zeitoun R (1985). Effects of andursil, ranitidine and prostaglandin E2 on indomethacin induced gastric ulcers in the rat. Annual Conference of the Egyptian Society of Pharmacology and Experimental Therapeutics, Alexandria, Egypt.